ArticleImplementation science communications2024
Development of a method for Making Optimal Decisions for Intervention Flexibility during Implementation (MODIFI): a modified Delphi study.
Article in Implementation science communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Best Practices for Integrating Early Relational Health Programs in Pediatric Primary Care: A Modified Delphi Process.Academic pediatrics · 2026Article
- Perspectives and Experiences of Nurses Implementing the Safe Steps for De-Escalation in Acute Mental Health Units.Journal of psychiatric and mental health nursing · 2026Article
- Identifying the Core Functions of a Health Insurance Literacy Program for Adolescent and Young Adult Cancer Survivors.Journal of adolescent and young adult oncology · 2026Article
- What counts as a core intervention component? Developing the Core-FAST (Fidelity and Adaptation for Scaling up Tool) plug-in.Implementation science communications · 2026Article
- Decision tree for improving the impact of equity-focused public health service delivery and research.Frontiers in health services · 2026Article
- Study Protocol - Assessing the feasibility of 'Screening by Accredited Social Health Activist (ASHAs) and diagnosis by Community Health officers of Asthma and COPD at the primary health care System- A Novel Strategy-Frontiers in health services · 2026Article
- Application of MODIFI to the adaptation of a complex, multilevel intervention to enhance access to high-quality cancer services in rural cancer hospitals.Implementation science communications · 2025Article
- Leveraging inter-organizational networks to scale up a sepsis recovery program: results from an application of the Making Optimal Decisions for Intervention Flexibility during Implementation (MODIFI) method.Implementation science communications · 2025Article
- Outcome preferences in fidelity-adaptation scenarios across evidence-based parenting programs: A discrete choice experiment.Implementation science : IS · 2025Article
- Implementation Science in School Mental Health: A 10-Year Progress Update and Development of a New Research Agenda.School mental health · 2024Article
Corrections and comments
- Update of
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntervention adaptation is often necessary to improve the fit between evidence-based practices/programs and implementation contexts. Existing frameworks describe intervention adaptation processes but do not provide detailed steps for prospectively designing adaptations, are designed for researchers, and require substantial time and resources to complete. A pragmatic approach to guide implementers through developing and assessing adaptations in local contexts is needed. The goal of this project was to develop Making Optimal Decisions for Intervention Flexibility during Implementation (MODIFI), a method for intervention adaptation that leverages human centered design methods and is tailored to the needs of intervention implementers working in applied settings with limited time and resources.
methodMODIFI was iteratively developed via a mixed-methods modified Delphi process. Feedback was collected from 43 implementation research and practice experts. Two rounds of data collection gathered quantitative ratings of acceptability and inclusion (Round 1) and feasibility (Round 2), as well as qualitative feedback regarding MODIFI revisions analyzed using conventional content analysis.
resultsIn Round 1, most participants rated all proposed components as essential but identified important avenues for revision which were incorporated into MODIFI prior to Round 2. Round 2 emphasized feasibility, where ratings were generally high and fewer substantive revisions were recommended. Round 2 changes largely surrounded operationalization of terms/processes and sequencing of content. Results include a detailed presentation of the final version of the three-step MODIFI method (Step 1: Learn about the users, local context, and intervention; Step 2: Adapt the intervention; Step 3: Evaluate the adaptation) along with a case example of its application. DISCUSSION: MODIFI is a pragmatic method that was developed to extend the contributions of other research-based adaptation theories, models, and frameworks while integrating methods that are tailored to the needs of intervention implementers. Guiding teams to tailor evidence-based interventions to their local context may extend for whom, where, and under what conditions an intervention can be effective.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.