Evidence map›Paper›PMID 38886812›Full record

ArticleAntimicrobial resistance and infection control2024

Dissemination of clinical Escherichia coli strains harboring mcr-1, bla

Lihua Liu, Mingqi Zhao, Yanhua Tang, Aihua Shen, Xiao Yang, Li Yao, Dongxing Tian

Abstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Characteristics ofOne health (Amsterdam, Netherlands) · 2026
    Article
  3. Review
  4. Polyclonal carbapenemase-producingFrontiers in cellular and infection microbiology · 2025
    Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lihua LiuDepartment of Clinical Laboratory, Affiliated Hospital of Jining Medical University, Jining, Shandong Province, China.
Mingqi ZhaoAffiliated Hospital of Jining Medical University, Jining, Shandong Province, China.
Yanhua TangDepartment of Respiratory and Critical Care Medicine, Affiliated Hospital of Jining Medical University, Jining, Shandong Province, China.
Aihua ShenDepartment of Clinical Laboratory, Affiliated Hospital of Jining Medical University, Jining, Shandong Province, China.
Xiao YangDepartment of Clinical Laboratory, Affiliated Hospital of Jining Medical University, Jining, Shandong Province, China.
Li YaoDepartment of Clinical Laboratory, Jining Wenshang Hospital, Jining, Shandong Province, China.
Dongxing TianDepartment of Clinical Laboratory, Affiliated Hospital of Jining Medical University, Jining, Shandong Province, China. dongxing0717@163.com.

Funding

China Postdoctoral Science Foundation 2022M721338Jining Key Research and Development Program 2021YXNS025Natural Science Foundation of Shandong Province ZR2023QH215Post-doctoral Program of Affiliated Hospital of Jining Medical University JYFY321208Project of Shandong Province Higher Educational Youth Innovation Science and Technology Program 2022KJ106Shandong Postdoctoral Innovation Talents Support Program SDBX2022052Tai Shan Young Scholar Foundation of Shandong Province tsqn202306400
6 · The paper itself

Abstract

backgroundCarbapenem-resistant E. coli (CREco) pose a significant public health threat due to their multidrug resistance. Colistin is often a last-resort treatment against CREco; however, the emergence of colistin resistance gene mcr-1 complicates treatment options.

methodsTwo E. coli strains (ECO20 and ECO21), recovered from hospitalized patients in distinct wards, exhibited resistance to carbapenems and colistin. Whole-genome sequencing and phenotypic characterization were employed to study resistance patterns, plasmid profiles, transferability of resistance and virulence genes, and siderophore production capabilities. Comparative genome analysis was used to investigate the genetic environment of mcr-1, bla

resultsBoth E. coli strains exhibited thr presence of both mcr-1 and bla

conclusionsOur findings underscore the co-occurrence of mcr-1, bla

Indexed as

Anti-Bacterial AgentsDrug Resistance, Multiple, BacterialEscherichia coliEscherichia coli InfectionsEscherichia coli ProteinsPlasmidsSiderophoresbeta-LactamasesCarbapenemsChinaColistinHospitalsHumansMicrobial Sensitivity TestsVirulence FactorsWhole Genome SequencingAnti-Bacterial Agentsbeta-LactamasesCarbapenemsColistinEscherichia coli ProteinsMCR-1 protein, E coliSiderophoresVirulence FactorsblaNDM-7Carbapenem-resistant EnterobacteralesEscherichia coliMcr-1Siderophore-producing plasmids

Identifiers

PMID38886812
PMCPMC11184858

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.