ArticleMalaria journal2024
LLIN evaluation in Uganda project (LLINEUP2): association between housing construction and malaria burden in 32 districts.
Article in Malaria journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Housing modification to prevent malaria in Uganda: an analysis of costs, willingness to pay, and equity.Malaria journal · 2025Trial
- Impact of indoor residual spraying and insecticide-treated nets on malaria burden in 8 districts in West Nile and Acholi regions, Uganda: a quasi-experimental study.BMC global and public health · 2026Article
- Hotspot Mapping, Spatiotemporal Clustering and Forecasting of Malaria Incidence in Uganda, 2014-2023: Strategies to Inform Targeted Public Health Interventions.Journal of epidemiology and global health · 2026Article
- Household and community-based approaches to malaria and cholera prevention: A narrative review with case studies from Uganda and Mozambique.PLoS neglected tropical diseases · 2026Review
- LLIN Evaluation in Uganda Project (LLINEUP2) - Effect of long-lasting insecticidal nets (LLINs) treated with pyrethroid plus pyriproxyfen vs LLINs treated with pyrethroid plus piperonyl butoxide in Uganda: A cluster-randomised trial.PLOS global public health · 2025Article
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Authors and funding
13 authors.
Funding
Abstract
backgroundWell-built housing limits mosquito entry and can reduce malaria transmission. The association between community-level housing and malaria burden in Uganda was assessed using data from randomly selected households near 64 health facilities in 32 districts.
methodsHouses were classified as 'improved' (synthetic walls and roofs, eaves closed or absent) or 'less-improved' (all other construction). Associations between housing and parasitaemia were made using mixed effects logistic regression (individual-level) and multivariable fractional response logistic regression (community-level), and between housing and malaria incidence using multivariable Poisson regression.
resultsBetween November 2021 and March 2022, 4.893 children aged 2-10 years were enrolled from 3.518 houses; of these, 1.389 (39.5%) were classified as improved. Children living in improved houses had 58% lower odds (adjusted odds ratio = 0.42, 95% CI 0.33-0.53, p < 0.0001) of parasitaemia than children living in less-improved houses. Communities with > 67% of houses improved had a 63% lower parasite prevalence (adjusted prevalence ratio 0.37, 95% CI 0.19-0.70, p < 0.0021) and 60% lower malaria incidence (adjusted incidence rate ratio 0.40, 95% CI 0.36-0.44, p < 0.0001) compared to communities with < 39% of houses improved.
conclusionsImproved housing was strongly associated with lower malaria burden across a range of settings in Uganda and should be utilized for malaria control.
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