Evidence map›Paper›PMID 38886451›Full record

ArticleScientific reports2024

Elucidating the function of STING in systemic lupus erythematosus through the STING Goldenticket mouse mutant.

Pichpisith Pierre Vejvisithsakul, Chisanu Thumarat, Asada Leelahavanichkul, Nattiya Hirankan, Trairak Pisitkun, Soren Riis Paludan, Prapaporn Pisitkun

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pichpisith Pierre VejvisithsakulProgram in Translational Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Chisanu ThumaratProgram in Translational Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Asada LeelahavanichkulDepartment of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Nattiya HirankanCentre of Excellent in Immunology and Immune-Mediated Diseases, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Trairak PisitkunCenter of Excellence in Systems Biology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Soren Riis PaludanDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0001-9180-4060
Prapaporn PisitkunProgram in Translational Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. Prapaporn.pis@mahidol.ac.th.

Funding

International Network for Lupus Research, IRN, Thailand IRN59W0004The Second Century Fund, Chulalongkorn University C2FThis research project was supported by the Faculty of Medicine Ramathibodi Hospital CF_65001
6 · The paper itself

Abstract

The complexity of systemic lupus erythematosus (SLE) arises from intricate genetic and environmental interactions, with STING playing a pivotal role. This study aims to comprehend the function of STING using the pristane-induced lupus (PIL) model in Sting missense mutant mice (Goldenticket or Sting

Indexed as

Disease Models, AnimalLupus Erythematosus, SystemicMembrane ProteinsAnimalsAntibodies, AntinuclearB-LymphocytesFemaleInterleukin-17Lupus NephritisMiceMutation, MissenseSTING ProteinTerpenesAntibodies, AntinuclearInterleukin-17Membrane ProteinspristaneSting1 protein, mouseSTING ProteinTerpenesMutationPristane-induced lupusSLESTINGTmem173

Identifiers

PMID38886451
PMCPMC11183220

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.