Evidence map›Paper›PMID 38886393›Full record

ArticleScientific data2024

Complete genome of the Listeria monocytogenes strain AUF, used as a live listeriosis veterinary vaccine.

Valentina A Feodorova, Sergey S Zaitsev, Mariya A Khizhnyakova, Maxim S Lavrukhin, Yury V Saltykov, Alexey D Zaberezhny, Olga S Larionova

Abstract readDataset
In one paragraph

Article in Scientific data, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Valentina A FeodorovaLaboratory for Fundamental and Applied Research, Saratov State University of Genetics, Biotechnology and Engineering named after N.I. Vavilov, Saratov, Russia. feodorovav@mail.ru.
Sergey S ZaitsevLaboratory for Fundamental and Applied Research, Saratov State University of Genetics, Biotechnology and Engineering named after N.I. Vavilov, Saratov, Russia.
Mariya A KhizhnyakovaLaboratory for Fundamental and Applied Research, Saratov State University of Genetics, Biotechnology and Engineering named after N.I. Vavilov, Saratov, Russia.
Maxim S LavrukhinLaboratory for Fundamental and Applied Research, Saratov State University of Genetics, Biotechnology and Engineering named after N.I. Vavilov, Saratov, Russia.
Yury V SaltykovLaboratory for Fundamental and Applied Research, Saratov State University of Genetics, Biotechnology and Engineering named after N.I. Vavilov, Saratov, Russia.
Alexey D ZaberezhnyAll-Russian Scientific Research and Technological Institute of Biological Industry, Biocombinat, Moscow, Russia.
Olga S LarionovaLaboratory for Fundamental and Applied Research, Saratov State University of Genetics, Biotechnology and Engineering named after N.I. Vavilov, Saratov, Russia.

Funding

Russian Science Foundation (RSF) 22-16-00165
6 · The paper itself

Abstract

Listeria monocytogenes (Lm) is a highly pathogenic bacterium that can cause listeriosis, a relatively rare food-borne infectious disease that affects farm, domestic, wild animals and humans as well. The infected livestock is the frequent sources of Lm. Vaccination is one of the methods of controlling listeriosis in target farm animals to prevent Lm-associated food contamination. Here we report the complete sequence of the Lm strain AUF attenuated from a fully-virulent Lm strain by ultraviolet irradiation, successfully used since the 1960s as a live whole-cell veterinary vaccine. The de novo assembled genome consists of a circular chromosome of 2,942,932 bp length, including more than 2,800 CDSs, 17 pseudogenes, 5 antibiotic resistance genes, and 56/92 virulence genes. Two wild Lm strains, the EGD and the 10403S that is also used in cancer Immunotherapy, were the closest homologs for the Lm strain AUF. Although all three strains belonged to different sequence types (ST), namely ST12, ST85, and ST1538, they were placed in the same genetic lineage II, CC7.

Indexed as

Genome, BacterialListeria monocytogenesListeriosisAnimalsBacterial VaccinesVaccines, AttenuatedBacterial VaccinesVaccines, Attenuated

Identifiers

PMID38886393
PMCPMC11183264

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.