Evidence map›Paper›PMID 38886003›Full record

ArticleRMD open2024

Rheumatoid arthritis and changes on spirometry by smoking status in two prospective longitudinal cohorts.

Keigo Hayashi, Gregory C McDermott, Pierre-Antoine Juge, Matthew Moll, Michael H Cho, Xiaosong Wang, Misti L Paudel, Tracy J Doyle, Gregory L Kinney, Danielle Sansone-Poe and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RMD open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Keigo HayashiDivision of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Gregory C McDermottDivision of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Pierre-Antoine JugeDivision of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, Massachusetts, USA.ORCID 0000-0002-3766-9600
Matthew MollHarvard Medical School, Boston, Massachusetts, USA.
Michael H ChoHarvard Medical School, Boston, Massachusetts, USA.
Xiaosong WangDivision of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Misti L PaudelDivision of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Tracy J DoyleHarvard Medical School, Boston, Massachusetts, USA.
Gregory L KinneyDepartment of Epidemiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Danielle Sansone-PoeDepartment of Epidemiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Kendra YoungDepartment of Epidemiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Paul F DellaripaDivision of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Zachary S WallaceHarvard Medical School, Boston, Massachusetts, USA.
Elizabeth A ReganNational Jewish Health, Denver, Colorado, USA.
Gary M HunninghakeHarvard Medical School, Boston, Massachusetts, USA.
Edwin K SilvermanHarvard Medical School, Boston, Massachusetts, USA.
Samuel Y AshSouth Shore Hospital, South Weymouth, MA, USA.
Raul San Jose EsteparHarvard Medical School, Boston, Massachusetts, USA.
George R WashkoHarvard Medical School, Boston, Massachusetts, USA.
Jeffrey A SparksDivision of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, Massachusetts, USA jsparks@bwh.harvard.edu.ORCID 0000-0002-5556-4618

Funding

Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
GENETIC EPIDEMIOLOGY OF COPD (COPD GENE) TASK A: STUDY VISIT 4, COLLECTION OF COPDGENE STUDY DATA ANDBIOSPECIMENS AND OVERSIGHT OF THE COPDGENE STUDY75N92023D00011 · NHLBI · NATIONAL JEWISH HEALTH · PI NEWMAN, LEE S · 2023 to 2025
$29.6M
Genetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7M
MECHANISMS OF ARTHRITIC &DERMATOLOGY DISORDERST32AR007530 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI Michael B. Brenner, Ellen M Gravallese · 1986 to 2026
$10.4M
VERITY: Value and Evidence in Rheumatology using bioInformaTics, and advanced analYticsP30AR072577 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI Daniel Hal Solomon · 2017 to 2026
$9.8M
Joint Biology Consortium Resource-based CenterP30AR070253 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI Peter A Nigrovic, Jeffrey Andrew Sparks · 2016 to 2026
$9.4M
Rheumatoid Arthritis-Related Autoantibodies, Articular Inflammation, and RA-Associated Interstitial Lung DiseaseR01AR077607 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI SPARKS, JEFFREY ANDREW · 2021 to 2025
$3.7M
Genetic and Functional Dissection of a Cluster of COPD GWAS Signals on Chromosome 4qR01HL147148 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CHO, MICHAEL H., SILVERMAN, EDWIN K · 2019 to 2022
$3.5M
Rheumatoid Arthritis-associated Parenchymal Lung Disease: Clinical and Molecular PhenotypesR01HL155522 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Jeffrey Andrew Sparks, George R Washko · 2022 to 2026
$3.5M
Clinical Implications, Genomics, and Transcriptions of Mucus Plugging in SmokersR01HL149861 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CHO, MICHAEL H., DIAZ, ALEJANDRO · 2020 to 2023
$3.2M
Immunologic and Clinical Sequelae after COVID-19 in Patients with Systemic Autoimmune Rheumatic DiseasesR01AR080659 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI Jeffrey Andrew Sparks · 2023 to 2026
$2.9M
Integrative genomic, transcriptomic and proteomic studies of pulmonary function and COPDR01HL153248 · NHLBI · UNIVERSITY OF VIRGINIA · PI CHO, MICHAEL H., MANICHAIKUL, ANI WANG · 2021 to 2024
$2.8M
CLC NIH HHS 75N90023D00011NHLBI NIH HHS 75N92021D00011NHLBI NIH HHS 75N92023D00011NHLBI NIH HHS K08 HL145118NHLBI NIH HHS R01 HL147148NHLBI NIH HHS R01 HL149861NHLBI NIH HHS R01 HL153248NHLBI NIH HHS R01 HL155522NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01 HL089897NIAID NIH HHS 75N93023D00011NIAMS NIH HHS K23 AR073334NIAMS NIH HHS P30 AR070253NIAMS NIH HHS P30 AR072577NIAMS NIH HHS R01 AR077607NIAMS NIH HHS R01 AR080659NIAMS NIH HHS T32 AR007530
6 · The paper itself

Abstract

objectiveTo compare longitudinal changes in spirometric measures between patients with rheumatoid arthritis (RA) and non-RA comparators.

methodsWe analysed longitudinal data from two prospective cohorts: the UK Biobank and COPDGene. Spirometry was conducted at baseline and a second visit after 5-7 years. RA was identified based on self-report and disease-modifying antirheumatic drug use; non-RA comparators reported neither. The primary outcomes were annual changes in the per cent-predicted forced expiratory volume in 1 s (FEV

resultsAmong participants who underwent baseline and follow-up spirometry, we identified 233 patients with RA and 37 735 non-RA comparators. Among never-smoking participants without an obstructive pattern, RA was significantly associated with more FEV

conclusionsSmokers with RA, especially those with baseline obstructive spirometric patterns, experienced lower FEV

Indexed as

Arthritis, RheumatoidSmokingSpirometryAdultAgedFemaleForced Expiratory VolumeHumansLongitudinal StudiesMaleMiddle AgedProspective StudiesPulmonary Disease, Chronic ObstructiveUnited KingdomVital CapacityPulmonary FibrosisRheumatoid ArthritisRisk FactorsSmoking

Identifiers

PMID38886003
PMCPMC11184187

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.