Evidence map›Paper›PMID 38886002›Full record

SynthesisRMD open2024

Synthesis of guidance available for assessing methodological quality and grading of evidence from qualitative research to inform clinical recommendations: a systematic literature review.

Mandeep Sekhon, Annette de Thurah, George E Fragoulis, Jan Schoones, Tanja A Stamm, Theodora P M Vliet Vlieland, Bente Appel Esbensen, Heidi Lempp, Lindsay Bearne, Marios Kouloumas and 6 more

Abstract readSystematic Review
In one paragraph

Synthesis in RMD open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Mandeep SekhonPopulation Health Research Institute, St George's University of London, London, UK msekhon@sgul.ac.uk.ORCID 0000-0002-5109-9536
Annette de ThurahDepartment of Rheumatology, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0003-0103-4328
George E FragoulisRheumatology, Army Shared Fund Hospital, Athens, Greece.ORCID 0000-0003-4932-7023
Jan SchoonesLeiden University Medical Center (LUMC), Directorate of research Policy, Leiden, Netherlands.
Tanja A StammSection for Outcomes Research, Medical University of Vienna, Vienna, Austria.ORCID 0000-0003-3073-7284
Theodora P M Vliet VlielandDept of Orthopaedics, Rehabilitation and Physical Therapy, Leiden University Medical Center (LUMC), Leiden, Netherlands.ORCID 0000-0001-6322-3859
Bente Appel EsbensenCopenhagen Center for Arthritis Research (Copecare), Rigshospitalet, Glostrup, Denmark.ORCID 0000-0001-5331-8221
Heidi LemppCentre for Rheumatic Diseases, Department of Inflammation Biology, School of Immunology and Microbial Sciences, Faculty of Life Sciences & Medicine, King's College London, London, UK.
Lindsay BearnePopulation Health Research Institute, St George's University of London, London, UK.
Marios KouloumasCyprus League Against Rheumatism, Aglantzia, Cyprus.
Polina PchelnikovaPARE Research Partner, EULAR, Zurich, Switzerland.
Thijs Willem SwinnenDivision of Rheumatology, KU Leuven University Hospitals Leuven, Leuven, Belgium.ORCID 0000-0002-5289-1023
Chris BluntLondon School of Economics and Political Science, London, UK.
Ricardo J O FerreiraNursing Research, Innovation and Development Centre of Lisbon (CIDNUR), Nursing School of Lisbon (ESEL), Lisbon, Portugal.ORCID 0000-0002-2517-0247
Loreto CarmonaInstituto de Salud Musculoesquelética, Madrid, Spain.ORCID 0000-0002-4401-2551
Elena NikiphorouCentre for Rheumatic Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK.ORCID 0000-0001-6847-3726

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo understand (1) what guidance exists to assess the methodological quality of qualitative research; (2) what methods exist to grade levels of evidence from qualitative research to inform recommendations within European Alliance of Associations for Rheumatology (EULAR).

methodsA systematic literature review was performed in multiple databases including PubMed/Medline, EMBASE, Web of Science, COCHRANE and PsycINFO, from inception to 23 October 2020. Eligible studies included primary articles and guideline documents available in English, describing the: (1) development; (2) application of validated tools (eg, checklists); (3) guidance on assessing methodological quality of qualitative research and (4) guidance on grading levels of qualitative evidence. A narrative synthesis was conducted to identify key similarities between included studies.

resultsOf 9073 records retrieved, 51 went through to full-manuscript review, with 15 selected for inclusion. Six articles described methodological tools to assess the quality of qualitative research. The tools evaluated research design, recruitment, ethical rigour, data collection and analysis. Seven articles described one approach, focusing on four key components to determine how much confidence to place in findings from systematic reviews of qualitative research. Two articles focused on grading levels of clinical recommendations based on qualitative evidence; one described a qualitative evidence hierarchy, and another a research pyramid.

conclusionThere is a lack of consensus on the use of tools, checklists and approaches suitable for appraising the methodological quality of qualitative research and the grading of qualitative evidence to inform clinical practice. This work is expected to facilitate the inclusion of qualitative evidence in the process of developing recommendations at EULAR level.

Indexed as

Qualitative ResearchResearch DesignEvidence-Based MedicineHumansPractice Guidelines as TopicHealth services researchPatient Reported Outcome MeasuresQualitative researchQuality Indicators, Health Care

Identifiers

PMID38886002
PMCPMC11184179

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.