Evidence map›Paper›PMID 38885220›Full record

Trial reportPloS one2024

Assessing the impact of jail-initiated medication for opioid use disorder: A multisite analysis of the SOMATICS collaborative.

Joshua D Lee, Keith Goldfeld, Robert P Schwartz, Ryan McDonald, Yifan Xu, Redonna Chandler, Kevin Hallgren, Sharon M Kelly, Shannon Gwinn Mitchell, Anjalee Sharma and 1 more

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Joshua D LeeDepartment of Population Health, NYU Grossman School of Medicine, New York City, NY, United States of America.
Keith GoldfeldDepartment of Population Health, NYU Grossman School of Medicine, New York City, NY, United States of America.
Robert P SchwartzFriends Research Institute, Baltimore, MD, United States of America.
Ryan McDonaldDepartment of Population Health, NYU Grossman School of Medicine, New York City, NY, United States of America.ORCID 0000-0001-5346-5336
Yifan XuDepartment of Population Health, NYU Grossman School of Medicine, New York City, NY, United States of America.
Redonna ChandlerNational Institute on Drug Abuse, Bethesda, MD, United States of America.
Kevin HallgrenDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, United States of America.
Sharon M KellyJohns Hopkins School of Medicine, Baltimore, MD, United States of America.
Shannon Gwinn MitchellFriends Research Institute, Baltimore, MD, United States of America.
Anjalee SharmaFriends Research Institute, Baltimore, MD, United States of America.ORCID 0000-0001-8872-4756
David FarabeeDepartment of Population Health, NYU Grossman School of Medicine, New York City, NY, United States of America.

Funding

Extended-Release Naltrexone Opioid Treatment at Jail-to-Community Re-entryU01DA033336 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LEE, JOSHUA D · 2013 to 2018
$3.5M
Depot Pharmacotherapies for Opioid-Dependent Offenders: Outcomes and CostsU01DA034743 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FARABEE, DAVID J · 2013 to 2016
$2.4M
A Randomized Trial of Interim Methadone and Patient Navigation Initiated in JailU01DA013636 · NIDA · FRIENDS RESEARCH INSTITUTE, INC. · PI SCHWARTZ, ROBERT P · 2013 to 2016
$2.4M
NIDA NIH HHS U01 DA013636NIDA NIH HHS U01 DA033336NIDA NIH HHS U01 DA034743
6 · The paper itself

Abstract

The objective of this study was to estimate the associations of jail-initiated medication for opioid use disorder (MOUD) and patient navigation (PN) with opioid use disorder (OUD) at 6 months post-release. Three randomized trials (combined N = 330) were combined to assess whether MOUD (extended-release naltrexone or interim methadone) initiated prior to release from jail with or without PN would reduce the likelihood of a DSM-5 diagnosis of OUD 6 months post-release relative to enhanced treatment-as-usual (ETAU). Across the three studies, assignment to MOUD compared to ETAU was not associated with an OUD diagnosis at 6 months post-release (69% vs. 75%, respectively, OR = 0.67, 95% CI: 0.42 to 1.20). Similarly, PN compared to MOUD without PN was not associated with an OUD diagnosis (63% vs 77%, respectively, OR = 0.61, 95% CI: 0.27 to 1.53). Results underscore the need to further optimize the effectiveness of MOUD for patients initiating treatment in jail, beginning with an emphasis on post-release treatment adherence.

Indexed as

MethadoneNaltrexoneOpioid-Related DisordersAdultFemaleHumansJailsMaleMiddle AgedNarcotic AntagonistsOpiate Substitution TreatmentPrisonersMethadoneNaltrexoneNarcotic Antagonists

Identifiers

PMID38885220
PMCPMC11182542

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.