Evidence map›Paper›PMID 38885091›Full record

ArticleACS chemical biology2024

Biosynthesis of

Jerry Cui, Kou-San Ju

Abstract read
In one paragraph

Article in ACS chemical biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Late-Stage Posttranslational Assembly of Fosfazinomycins.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jerry CuiDepartment of Microbiology, The Ohio State University, Columbus, Ohio 43210, United States.ORCID 0000-0002-8165-7340
Kou-San JuDepartment of Microbiology, The Ohio State University, Columbus, Ohio 43210, United States.ORCID 0000-0003-0438-6740

Funding

Genomics-Accelerated Discovery and Biosynthesis of Phosphonic Acid Natural ProductsR01GM137135 · NIGMS · OHIO STATE UNIVERSITY · PI JU, KOU-SAN · 2020 to 2024
$1.7M
NIGMS NIH HHS R01 GM137135
6 · The paper itself

Abstract

Phosphonate natural products have a history of commercial success across numerous industries due to their potent inhibition of metabolic processes. Over the past decade, genome mining approaches have successfully led to the discovery of numerous bioactive phosphonates. However, continued success is dependent upon a greater understanding of phosphonate metabolism, which will enable the prioritization and prediction of biosynthetic gene clusters for targeted isolation. Here, we report the complete biosynthetic pathway for phosphonoalamides E and F, antimicrobial phosphonopeptides with a conserved

Indexed as

BacillusOrganophosphonatesAmino AcidsBacterial ProteinsBiosynthetic PathwaysLigasesMultigene FamilySubstrate SpecificityAmino AcidsBacterial ProteinsLigasesOrganophosphonates

Identifiers

PMID38885091
PMCPMC11259534

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.