Evidence map›Paper›PMID 38884976›Full record

ArticleHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2024

Adverse childhood experiences and adult disease: Examining mediating pathways in the Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study.

Marissa A Kobayashi, Carmen R Isasi, Shakira F Suglia, Linda C Gallo, Angela P Gutierrez, Daniela Sotres-Alvarez, Maria M Llabre

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Article in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marissa A KobayashiDepartment of Psychology, University of Miami.ORCID 0000-0001-7475-0785
Carmen R IsasiDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine.
Shakira F SugliaDepartment of Epidemiology, Emory University.
Linda C GalloDepartment of Psychology, San Diego State University.
Angela P GutierrezDepartment of Psychiatry, University of California, San Diego.
Daniela Sotres-AlvarezCollaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina, Chapel Hill.
Maria M LlabreDepartment of Psychology, University of Miami.

Funding

New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
Ancillary to HCHS/SOL: Sociocultural Factors and CVD risk/prevalence in HispanicsRC2HL101649 · NHLBI · SAN DIEGO STATE UNIVERSITY · PI GALLO, LINDA C, LLABRE, MARIA MAGDALENA · 2009 to 2010
$4.7M
HISPANIC COMMUNITY HEALTH STUDY-268065233N01HC065233 · HC · COORDINATING CENTER · PI CHAMBLESS, LLOYD E · 2006 to 2006
–
National Institutes of Health; National Heart, Lung, and Blood InstituteNHLBI NIH HHS N01 HC065233NHLBI NIH HHS N01 HC065234NHLBI NIH HHS N01 HC065235NHLBI NIH HHS N01 HC065236NHLBI NIH HHS N01 HC065237NHLBI NIH HHS RC2 HL101649NIDDK NIH HHS P30 DK111022
6 · The paper itself

Abstract

objectivesAdverse childhood experiences (ACEs) have been linked to adulthood chronic diseases, but there is little research examining the mechanisms underlying this association. We tested pathways from ACEs to adult disease mediated via risk factors of depression, smoking, and body mass index.

methodProspective data from adults 18 to 74 years old from the Hispanic Community Health Study/Study of Latinos and Sociocultural Ancillary Study were used. Retrospectively reported ACEs and hypothesized mediators were measured at Visit 1 (2008-2011). Outcomes of disease prevalence were assessed at Visit 2, approximately 6 years later. The analytic sample includes 5,230 Hispanic/Latino participants with ACE data. Statistical mediation was examined using structural equation modeling on cardiometabolic and pulmonary disease prevalence and reported probit regression coefficients with 95% confidence intervals (CIs).

resultsWe found a significant association between ACEs and the prevalence of asthma/chronic obstructive pulmonary disorder (standardized β = .07, 95% CI [0.02, 0.12]). In the mediational model, the direct association was nonsignificant (β = .02, 95% CI [-0.04, 0.07]) but was mediated by depressive symptoms (β = .03, 95% CI [0.02, 0.04]). There were no associations between ACEs and the prevalence of diabetes and self-reported coronary heart disease or cerebrovascular disease. However, a small indirect effect was identified via depressive symptoms and coronary heart disease (β = .02, 95% CI [0.01, 0.03]).

conclusionIn this diverse Hispanic/Latino sample, depressive symptoms were found to be a pathway linking ACEs to self-reported cardiopulmonary diseases, although the effects were of small magnitude. Future work should replicate pathways, confirm the magnitude of effects, and examine cultural moderators that may dampen expected associations. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Indexed as

Adverse Childhood ExperiencesHispanic or LatinoAdolescentAdultAgedAsthmaBody Mass IndexChronic DiseaseDepressionFemaleHumansMaleMiddle AgedPrevalenceProspective StudiesPulmonary Disease, Chronic Obstructive

Identifiers

PMID38884976
PMCPMC12004413

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.