Evidence map›Paper›PMID 38884139›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Engineered Bacteria as Living Biosensors in Dermal Tattoos.

Matthew E Allen, Elina Kamilova, Carolina Monck, Francesca Ceroni, Yubing Hu, Ali K Yetisen, Yuval Elani

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Biofilms: from the cradle of life to life support.NPJ biofilms and microbiomes · 2026
    Review
  4. Article
  5. Article
  6. Probiotic-Based Materials as Living Therapeutics.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  7. Article
  8. Engineered Bacteria as Living Biosensors in Dermal Tattoos.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Matthew E AllenDepartment of Chemistry, Imperial College London, Molecular Sciences Research Hub, London, W12 0BZ, UK.ORCID 0000-0002-4501-6327
Elina KamilovaDepartment of Chemical Engineering, Imperial College London, South Kensington, London, SW7 2AZ, UK.
Carolina MonckDepartment of Chemical Engineering, Imperial College London, South Kensington, London, SW7 2AZ, UK.
Francesca CeroniDepartment of Chemical Engineering, Imperial College London, South Kensington, London, SW7 2AZ, UK.
Yubing HuDepartment of Chemical Engineering, Imperial College London, South Kensington, London, SW7 2AZ, UK.
Ali K YetisenDepartment of Chemical Engineering, Imperial College London, South Kensington, London, SW7 2AZ, UK.
Yuval ElaniInstitute of Chemical Biology, Imperial College London, Molecular Sciences Research Hub, London, W12 0BZ, UK.ORCID 0000-0002-9603-2490

Funding

Biotechnology and Biological Sciences Research Council BB/W00125X/1Medical Research Council MR/S031537/1UK Research and Innovation MR/S031537/1
6 · The paper itself

Abstract

Dermal tattoo biosensors are promising platforms for real-time monitoring of biomarkers, with skin used as a diagnostic interface. Traditional tattoo sensors have utilized small molecules as biosensing elements. However, the rise of synthetic biology has enabled the potential employment of engineered bacteria as living analytical tools. Exploiting engineered bacterial sensors will allow for potentially more sensitive detection across a broad biomarker range, with advanced processing and sense/response functionalities using genetic circuits. Here, the interfacing of bacterial biosensors as living analytics in tattoos is shown. Engineered bacteria are encapsulated into micron-scale hydrogel beads prepared through scalable microfluidics. These biosensors can sense both biochemical cues (model biomarkers) and biophysical cues (temperature changes, using RNA thermometers), with fluorescent readouts. By tattooing beads into skin models and confirming sensor activity post-tattooing, our study establishes a foundation for integrating bacteria as living biosensing entities in tattoos.

Indexed as

Biosensing TechniquesTattooingBacteriaBiomarkersHumansSkinBiomarkersbacteriabiosensorshydrogelsmicrofluidicssynthetic biologytattoo

Identifiers

PMID38884139
PMCPMC11321667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.