Evidence map›Paper›PMID 38884080›Full record

ArticleFrontiers in oncology2024

Gut microbiota and oral cavity cancer: a two-sample bidirectional Mendelian randomization study.

Zhijuan Sun, Chunying Bai, Dandan Hao, Xiling Jiang, Jianxing Chen

Abstract read
In one paragraph

Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. IntratumoralAnimals : an open access journal from MDPI · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhijuan SunInternational Education School, Chifeng University, Chifeng, China.
Chunying BaiSchool of Basic Medical Sciences, Chifeng University, Chifeng, China.
Dandan HaoSchool of Basic Medical Sciences, Chifeng University, Chifeng, China.
Xiling JiangDepartment of Stomatology, Affiliated Hospital of Chifeng University, Chifeng, China.
Jianxing ChenInternational Education School, Chifeng University, Chifeng, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study employs a two-sample bidirectional Mendelian randomization (MR) approach to systematically evaluate the causal relationship between gut microbiota and oral cavity cancer (OCC). Objective: To address the challenge in establishing the causal relationship between gut microbiota and OCC, we applied a systematic MR analysis. Methods: Utilizing GWAS data from the MiBioGen consortium (18,340 individuals) and UK Biobank (n = 264,137), we selected instrumental variables and employed MR-Egger, weighted median, IVW, and weighted mode analyses. Heterogeneity and pleiotropy were assessed using Cochran's Q test and MR-Egger intercept test. Results: Our findings indicate, at the order level, Conclusion: Our study identifies

Indexed as

causalitygut microbiotaGWASMendelian randomizationoral cavity cancer

Identifiers

PMID38884080
PMCPMC11177610

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.