ArticleFrontiers in oncology2024
A life-threatening, massive subcutaneous hematoma caused by trauma in a patient with neurofibromatosis type 1: a case report and literature review.
Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Recurrent spontaneous cervical hemorrhage in a patient with neurofibromatosis type 1 requiring repeated endovascular embolization: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Comprehensive perioperative management of a giant neurofibroma complicated by hemorrhagic shock: a case report.Frontiers in surgery · 2026Article
- Outcome of Surgical Intervention in Giant Neurofibromas in Two Sisters with Neurofibromatosis Type 1: A Case Series and Literature Review.Clinical, cosmetic and investigational dermatology · 2026Article
- Spontaneous peripheral artery rupture in patients with neurofibromatosis type 1.Journal of vascular surgery cases and innovative techniques · 2025Article
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Authors and funding
9 authors.
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Abstract
Background: Neurofibromatosis type 1 (NF1) is an autosomal dominant disease that can give rise to the formation of vascular lesions in affected individuals. These lesions, whether occurring spontaneously or as a result of trauma, have the potential to cause severe and even fatal hemorrhage. Case description: We presented a case demonstrating the most extensive hematoma ever documented in a patient with NF1, resulting from a minor trauma. He experienced hemodynamic instability due to severe anemia. Arteriography revealed a rupture in the intercostal artery, which was successfully treated through interventional embolization to stop the hemorrhage. Additionally, we implemented a refined surgical approach, beginning with suturing, followed by the meticulous resection of necrotic and aberrant tissues, thereby markedly diminishing bleeding. Conclusion: Minor trauma may cause severe bleeding in patients with NF1, which can be life-threatening. Timely diagnosis of NF1 and effective hemostatic techniques are key to successful treatment.
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