Evidence map›Paper›PMID 38883936›Full record

ArticleAnnals of surgery open : perspectives of surgical history, education, and clinical approaches2024

Stapled End-To-Side Ileocolic Anastomosis in Crohn's Disease: Old Dog, Reliable Tricks? A Retrospective Two-Center Cohort Study.

Volkan Doğru, Jean H Ashburn, Umut Akova, Alton G Sutter, Eren Esen, Emily M Gardner, Andre da Luz Moreira, Arman Erkan, John Kirat, Michael J Grieco and 1 more

Abstract read
In one paragraph

Article in Annals of surgery open : perspectives of surgical history, education, and clinical approaches, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Volkan DoğruFrom the Inflammatory Bowel Disease Center, NYU Langone Health, New York, NY.
Jean H AshburnDepartment of Surgery, Wake Forest University Baptist Health, Winston-Salem, NC.
Umut AkovaFrom the Inflammatory Bowel Disease Center, NYU Langone Health, New York, NY.
Alton G SutterDepartment of Surgery, Wake Forest University Baptist Health, Winston-Salem, NC.
Eren EsenFrom the Inflammatory Bowel Disease Center, NYU Langone Health, New York, NY.
Emily M GardnerDepartment of Surgery, Wake Forest University Baptist Health, Winston-Salem, NC.
Andre da Luz MoreiraFrom the Inflammatory Bowel Disease Center, NYU Langone Health, New York, NY.
Arman ErkanFrom the Inflammatory Bowel Disease Center, NYU Langone Health, New York, NY.
John KiratFrom the Inflammatory Bowel Disease Center, NYU Langone Health, New York, NY.
Michael J GriecoFrom the Inflammatory Bowel Disease Center, NYU Langone Health, New York, NY.
Feza H RemziFrom the Inflammatory Bowel Disease Center, NYU Langone Health, New York, NY.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Analyze our long-term experience with a less-popularized but stalwart approach, the stapled end-to-side ileocolic anastomosis. Background: The choice of technical approach to ileocolic anastomosis after ileocecal resection for Crohn's disease affects surgical outcomes and recurrence. Yet, despite heterogeneous data from different anastomotic configurations, there remains no clear guidance as to the optimal technique. Methods: In a retrospective cohort design, patients undergoing ileocolic anastomosis in the setting of Crohn's disease between 2016 and 2021 at two institutions were identified. Patient characteristics and surgical outcomes in terms of recurrence (surgical, clinical, and endoscopic) were studied. Results: In total, 211 patients were included. Before surgery, 80% were exposed to at least 1 cycle of systemic steroids and 71% had at least 1 biologic agent; 60% exhibited penetrating disease and 38% developed an intra-abdominal abscess. After surgery, one anastomosis leaked (0.5%). Over 2.4 years of follow-up (IQR = 1.3-3.9), surgical recurrence was 0.9%. Two-year overall recurrence-free and endoscopic recurrence-free survivals were 74% and 85% (95% CI = 68-81 and 80-91), respectively. The adjusted hazard ratio of endoscopic recurrence was 3.0 (95% CI = 1.4-6.2) for males and 5.2 (1.2-22) for patients who received systemic steroids before the surgery. Conclusion: The stapled end-to-side anastomosis is an efficient, reliable, and reproducible approach to maintain bowel continuity after ileocecal resection with durable outcomes. Our outcomes demonstrate low rates of disease recurrence and stand favorably in comparison to other more technically complex or protracted anastomotic approaches. This anastomosis is an ideal reconstructive approach after ileocecal resection for Crohn's disease.

Indexed as

Crohn’s diseaseileocolic anastomosispostoperative recurrence

Identifiers

PMID38883936
PMCPMC11175959

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.