ArticleiScience2024
Social status predicts physiological and behavioral responses to chronic stress in rhesus monkeys.
Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Social hierarchy shapes behavioral and transcriptional responses to chronic stress and ketamine in male mice.iScience · 2026Article
- Succession Dominates Alpha Male Replacement in Despotic Rhesus Monkeys: Insights from a Long-Term Study in the Taihang Mountains, Henan Province, China.Animals : an open access journal from MDPI · 2026Article
- Longitudinal Characterization of GiantResearch (Washington, D.C.) · 2026Article
- Effect of Relocation, Social Housing Changes, and Diarrhea Status on Microbiome Composition of Juvenile Cynomolgus Macaques (Microorganisms · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Investigating the underlying factors that cause differential individual responses to chronic stress is crucial for developing personalized therapies, especially in the face of pandemics such as COVID-19. However, this question remains elusive, particularly in primates. In the present study, we aimed to address this question by utilizing monkeys as a model to examine the impacts of social rank on stress levels and physiological and behavioral responses to chronic stress primarily caused by social isolation at both the individual and group levels. Our results showed that high-ranking animals were more susceptible to chronic stress. After exposure to chronic stress, although social hierarchies remained the same, the colonies exhibited more harmonious group relationships (e.g., more prosocial behaviors), with notable contributions from low-ranking animals. Overall, this study deepens our understanding of how social status shapes responses to chronic stress and sheds light on developing tailored and personalized therapies for coping with chronic stress.
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Registered trials
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