Evidence map›Paper›PMID 38883644›Full record

ArticleJournal of thoracic disease2024

Integrated endoscopic treatment of primitive unresectable tracheal tumor: the INTACT retrospective cohort study.

Alessandro Marchioni, Linda Manicardi, Roberto Tonelli, Luca Tabbì, Dario Andrisani, Antonio Lamesta, Anna Mocellin, Giulia Bruzzi, Gaia Cappiello, Alessandro Andreani and 3 more

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alessandro Marchioni *Respiratory Diseases Unit, University Hospital of Modena, Modena, Italy.ORCID https://orcid.org/0000-0003-3720-3517
Linda Manicardi *Respiratory Diseases Unit, University Hospital of Modena, Modena, Italy.
Roberto TonelliRespiratory Diseases Unit, University Hospital of Modena, Modena, Italy.
Luca TabbìRespiratory Diseases Unit, University Hospital of Modena, Modena, Italy.
Dario AndrisaniRespiratory Diseases Unit, University Hospital of Modena, Modena, Italy.
Antonio LamestaThoracic Surgery Unit, University Hospital of Modena, Modena, Italy.
Anna MocellinRespiratory Diseases Unit, University Hospital of Modena, Modena, Italy.
Giulia BruzziRespiratory Diseases Unit, University Hospital of Modena, Modena, Italy.
Gaia CappielloRespiratory Diseases Unit, University Hospital of Modena, Modena, Italy.
Alessandro AndreaniPneumology Unit, Santa Maria Bianca Hospital of Mirandola, Modena, Italy.
Francesco MattioliOthorinolaringoiatry, University Hospital of Modena, Modena, Italy.
Pierluigi Filosso *Thoracic Surgery Unit, University Hospital of Modena, Modena, Italy.
Enrico Clini *Respiratory Diseases Unit, University Hospital of Modena, Modena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Primitive tracheal tumors represent a rare entity whose management, when unresectable, remains challenging. Primary aim of this study was to explore the survival and the factors influencing prognosis of patients with unresectable primitive tracheal tumor undergoing multimodal treatment integrating interventional bronchoscopy and radiotherapy. Methods: This retrospective cohort study was conducted at the University Hospital of Modena (Italy) over a 12-year period (January 2010 to January 2022) analyzing patients with unresectable primary tracheal tumor receiving interventional bronchoscopy treatment followed by radiotherapy. Survival analysis was conducted for the whole population and according to histology, development of metastasis, stent placement and the onset of disease relapse. The raw and independent association between potential risk factor and 5-year mortality and the reported complications were investigated. Results: A total of 12 patients were included. Five-year survival rate was 42% with a median survival time of 26.7 (interquartile range, 4.1-82) months. Survivors showed a higher prevalence of cystic-adenoid histology (80% Conclusions: Multimodal treatment including interventional bronchoscopy and associated radiotherapy for unresectable primary tracheal tumors seems not burdened by significant complications and may provide benefits in terms of survival for those patients with cystic-adenoid histology.

Indexed as

cystic-adenoid histologyPrimitive tracheal tumorrigid bronchoscopysquamous-cell carcinomatracheal stent

Identifiers

PMID38883644
PMCPMC11170399

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.