Evidence map›Paper›PMID 38883403›Full record

ArticleGMS hygiene and infection control2024

Incidence of side effects of antituberculosis drugs and their related factors in northern Iran: a retrospective cohort study.

Motahareh Kheradmand, Mahdi Afshari, Mohsen Aarabi, Siavosh Abedi, Mohammadreza Parsaee, Asghar Nezammahalleh, Mahmood Moosazadeh

Abstract read
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Article in GMS hygiene and infection control, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Motahareh KheradmandHealth Sciences Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran.
Mahdi AfshariPediatric Gastroenterology and Hepatology Research Center, Zabol University of Medical Sciences, Zabol, Iran.
Mohsen AarabiDepartment of Family Medicine, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Siavosh AbediDepartment of Internal Medicine, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Mohammadreza ParsaeeHealth deputy, Mazandaran University of Medical Sciences, Sari, Iran.
Asghar NezammahallehHealth deputy, Mazandaran University of Medical Sciences, Sari, Iran.
Mahmood MoosazadehGastrointestinal Cancer Research Center, Non-communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Antituberculosis drugs may cause mild, moderate or severe adverse drug reactions (ADR) leading to poor compliance. Description of the pattern of ADR and their related factors can help tuberculosis (TB) control program as part of the WHO programs. This study aims to investigate the incidence of ADR and associated factors among TB patients in northern Iran. Methods: This is a retrospective cohort study. The required information, including year of diagnosis, age, gender, residence area, nationality, HIV co-morbidity, history of anti TB treatment and ADR, was obtained from the Deputy of Health, Mazandaran University of Medical Sciences, Iran. All data were analyzed using SPSS version 21 software. Results: Out of 3903 TB patients, 136 (3.5%) experienced major ADR. The incidence of ADR for men and women as well as for those with and without previous treatment history were 3.9% vs. 3.3% and 5.3% vs. 3.4%, respectively (p>0.05). Multiple logistic regression models showed a higher chance of ADR among those aged over 59 compared with those aged under 29 (OR=2.63, 95% confidence interval: 1.54-4.49). Conclusions: Age over 59 can be considered a risk factor for ADR with anti-TB drug administration.

Indexed as

adverse drug reactionantituberculosis drugsrisk factor

Identifiers

PMID38883403
PMCPMC11177222

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