Evidence map›Paper›PMID 38883011›Full record

ArticleCureus2024

Persistent Peril: Recurrent Deep Vein Thrombosis and Pulmonary Embolism in a Patient With Protein S Deficiency Despite Optimal Anticoagulation Therapies.

Ali Ghorbani, Jamie Greathouse, Sina Bakhshaei, Aida Ghorbani, Kurosh Zamiri, Lauren Ho, Andrew Ho

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ali GhorbaniInternal Medicine, Southwest Healthcare, Temecula, USA.
Jamie GreathouseInternal Medicine, Temecula Valley Hospital, Temecula, USA.
Sina BakhshaeiInternal Medicine, Southern California Medical Education Consortium, Temecula Valley Hospital, Temecula, USA.
Aida GhorbaniNeurology, UCLA School of Medicine, Los Angeles, USA.
Kurosh ZamiriBiology, University of California Los Angeles, Los Angeles, USA.
Lauren HoCardiology, Temecula Valley Hospital, Temecula, USA.
Andrew HoCardiology, Temecula Valley Hospital, Temecula, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The clotting system has evolved as an adaptive mechanism to prevent blood loss during vascular damage. However, the intricate nature of the clotting cascade and the complexities of human life can sometimes lead to the unnatural activation of this delicate cascade. This can result in blood clot formation within the cardiovascular system, contributing to a wide range of pathological conditions. Abnormal intravascular coagulation most commonly occurs in the deep veins of the lower extremities, and can emboli to other organs, hence, it is termed "venous thromboembolism" (VTE). In this report, we introduce a challenging case of VTE that poses a dilemma for current medical management. The patient with possible protein S deficiency underwent various guideline-directed medical treatments, yet experienced recurrent VTE episodes, including deep vein thrombosis (DVT) and pulmonary embolism (PE), leading to hospital readmissions. This case report sheds light on our challenges in effectively treating VTE.

Indexed as

acute hypoxemic respiratory failureapixabandeep vein thrombosis (dvt)hereditary protein s deficiencyhereditary thrombophiliahypercoagulable staterecurrent dvtrecurrent peright heart strainsubmassive pulmonary embolism

Identifiers

PMID38883011
PMCPMC11180491

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.