Evidence map›Paper›PMID 38882835›Full record

ReviewJournal of pharmacy & bioallied sciences2024

Factors Affecting the Availability and Utilization of Essential Medicines in India: A Systematic Review.

Medha Wadhwa, Poonam Trivedi, Devang Raval, Somen Saha, Hitesh Prajapati, Rupal Gautam, K V Jagadeesh, Kavitha Rajshekhar

Abstract readReview
In one paragraph

Review in Journal of pharmacy & bioallied sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Medha WadhwaDepartment of Health Policy, Management and Behavioural Science, Indian Institute of Public Health, Gandhinagar, Gujarat, India.
Poonam TrivediRegional Resource Centre for Health Technology Assessment, Indian Institute of Public Health, Gandhinagar, Gujarat, India.
Devang RavalRegional Resource Centre for Health Technology Assessment, Indian Institute of Public Health, Gandhinagar, Gujarat, India.
Somen SahaDepartment of Public Health Program, Indian Institute of Public Health Gandhinagar, Gujarat, India.
Hitesh PrajapatiGujarat Medical Services Corporation Limited, Gandhinagar, Gujarat, India.
Rupal GautamGujarat Medical Services Corporation Limited, Gandhinagar, Gujarat, India.
K V JagadeeshDepartment of Health Research HTAIn Secretariat, India.
Kavitha RajshekharDepartment of Health Research HTAIn Secretariat, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Essential medicines or drugs are recognized as highly cost-effective components within contemporary healthcare, demonstrating significant potential for improving health outcomes. The provision of essential medicines directly impacts the functioning of healthcare facilities, resulting in financial hardship. This review aims to fill knowledge gaps by examining obstacles hindering access and utilization of essential medicines in India. This study conducted a comprehensive evidence synthesis, following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, to analyse articles on the availability and utilization of essential medicines in India. The search strategy included various databases and keywords. Published, peer-reviewed articles focusing on the National/ State List of Essential Medicines and meeting specific criteria were considered. Data items included essential medicines, drug availability, utilization, and challenges. Data was extracted, synthesized, and analysed using thematic framework analysis. Out of 1,129 articles, 11 were selected for review. Studies consistently highlighted the inadequate availability of essential medicines in different Indian states. Availability of essential medicines varies in the range of 17-51 percent across major states of India. Stock-outs of medicines vary from 4 to 14 weeks. Governance issues including differential procurement mechanisms across states of India, hinder seamless availability of essential medicines. Other challenges included distribution and purchasing system inefficiencies, governance-related issues, and facility/ user-level challenges impacting drug utilization. Disruptions in utilization were observed due to improper prescription practices and non-availability of affordable options. Accessibility and affordability also affected drug utilization. Issues with supply chain management and conflicting guidelines further contributed to the obstacles faced in ensuring availability and utilization of essential medicines in India. Ensuring the availability, accessibility, and affordability of essential medicines is of utmost importance. The public health system needs to strengthen its procurement and distribution management. Strengthening the logistics support for an efficient supply of essential medicines will reduce the time lag in receipt of drugs. Guidelines on essential drugs prepared by the National Health System Resource Centre need to be strictly adhered to and monitored in inventory management system. There is an urgent need to develop a sustainable model for achieving uniformity in the availability and utilization of essential medicines in India.

Indexed as

Availabilitychallengesessential drugsIndiautilization

Identifiers

PMID38882835
PMCPMC11174260

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.