Evidence map›Paper›PMID 38882590›Full record

ArticleAmerican heart journal plus : cardiology research and practice2024

Racial differences in baroreflex function: Implications for the cardiovascular conundrum.

DeWayne P Williams, Cameron R Wiley, Julia Birenbaum, Grace M Fishback, Lassiter F Speller, Julian Koenig, Marc Jarczok, Gaston Kapuku, Gustavo A Reyes Del Paso, LaBarron K Hill and 1 more

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In one paragraph

Article in American heart journal plus : cardiology research and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The physiological cost of coping: a systematic review and meta-analysis on discrimination and heart rate variability.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2026
    Pooled it
  2. Guidelines for rigor and reproducibility of heart rate variability within human cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2026
    Review
  3. Article
  4. Article
  5. Cardiac autonomic function in young, healthy adults: Influence of race and sex.American journal of physiology. Regulatory, integrative and comparative physiology · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

DeWayne P WilliamsDepartment of Psychological Science, University of California, Irvine, USA.
Cameron R WileyDepartment of Psychological Science, University of California, Irvine, USA.
Julia BirenbaumDepartment of Psychological Science, University of California, Irvine, USA.
Grace M FishbackDepartment of Psychological Science, University of California, Irvine, USA.
Lassiter F SpellerDepartment of Psychology and Political Science, Eastern New Mexico University, Portales, NM, USA.
Julian KoenigUniversity of Cologne, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Germany.
Marc JarczokMannheim Institute of Public Health, Social and Preventive Medicine, Mannheim Medical Faculty, Heidelberg University, Mannheim, Germany.
Gaston KapukuDepartment of Medicine, Georgia Prevention Institute, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Gustavo A Reyes Del PasoDepartment of Psychology, University of Jaén, Jaén, Spain.
LaBarron K HillDepartment of Psychology, North Carolina Agricultural and Technical State University, Greensboro, NC, USA.
Julian F ThayerDepartment of Psychological Science, University of California, Irvine, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Study objective: African Americans (AAs) show early signs of vascular dysfunction paired with elevated blood pressure (BP) and total peripheral resistance (TPR), which is thought to underlie their increased rates of cardiovascular health complications relative to European Americans (EAs). AAs paradoxically have higher cardiac vagal tone, indexed by heart rate variability (HRV), which is cardio-protective. This paradox has been termed the Design: Participants completed a 5-minute baseline period where resting cardiac metrics were assessed. Setting: Laboratory. Participants: 130 college-aged individuals (54 women, 57 AAs). Main outcome measures: Baroreflex function was indexed as baroreflex sensitivity (BRS; the magnitude of changes in cardiovascular activity in accordance with BP changes) and effectiveness (BEI; the ratio of BP changes that elicit changes in cardiovascular activity) in the cardiac, vascular, and myocardial limbs. Results and conclusions: Results showed AAs to have higher HRV and cardiac BRS in comparison to EAs, suggesting the baroreflex is more sensitive to correcting the heart period for changes in BP among AAs compared to EAs. However, AAs showed lower vascular BEI relative to EAs, suggesting less effective control of TPR. In sum, lower BEI in the vascular branch might be an important mechanism underlying the

Indexed as

BaroreceptorBaroreflexBlood pressureEthnic differencesTotal peripheral resistance

Identifiers

PMID38882590
PMCPMC11177048

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.