Evidence map›Paper›PMID 38882494›Full record

ArticleiMeta2024

Infant age inversely correlates with gut carriage of resistance genes, reflecting modifications in microbial carbohydrate metabolism during early life.

Xinming Xu, Qingying Feng, Tao Zhang, Yunlong Gao, Qu Cheng, Wanqiu Zhang, Qinglong Wu, Ke Xu, Yucan Li, Nhu Nguyen and 8 more

Abstract read
In one paragraph

Article in iMeta, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Xinming XuLaboratory of Gastrointestinal Microbiology, College of Animal Science & Technology Nanjing Agricultural University Nanjing China.ORCID 0009-0005-3121-8138
Qingying FengLaboratory of Gastrointestinal Microbiology, College of Animal Science & Technology Nanjing Agricultural University Nanjing China.
Tao ZhangLaboratory of Gastrointestinal Microbiology, College of Animal Science & Technology Nanjing Agricultural University Nanjing China.
Yunlong GaoLaboratory of Gastrointestinal Microbiology, College of Animal Science & Technology Nanjing Agricultural University Nanjing China.
Qu ChengDepartment of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College Huazhong University of Science and Technology Wuhan China.
Wanqiu ZhangLaboratory of Gastrointestinal Microbiology, College of Animal Science & Technology Nanjing Agricultural University Nanjing China.
Qinglong WuDepartment of Pathology and Immunology Baylor College of Medicine Houston Texas USA.ORCID 0000-0003-3473-075X
Ke XuDepartment of Statistics University of Chicago Chicago Illinois.
Yucan LiState Key Laboratory of Genetic Engineering, Human Phenome Institute Fudan University Shanghai China.
Nhu NguyenDepartment of Food Science and Technology University of California, Davis Davis California USA.
Diana H TaftDepartment of Food Science and Technology University of California, Davis Davis California USA.
David A MillsDepartment of Food Science and Technology University of California, Davis Davis California USA.
Danielle G LemayUSDA ARS Western Human Nutrition Research Center Davis California USA.
Weiyun ZhuLaboratory of Gastrointestinal Microbiology, College of Animal Science & Technology Nanjing Agricultural University Nanjing China.
Shengyong MaoLaboratory of Gastrointestinal Microbiology, College of Animal Science & Technology Nanjing Agricultural University Nanjing China.
Anyun ZhangAnimal Disease Prevention and Food Safety Key Laboratory of Sichuan Province, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences Sichuan University Chengdu China.
Kelin XuDepartment of Biostatistics, Key Laboratory of Public Health Safety, NHC Key Laboratory of Health Technology Assessment, School of Public Health Fudan University Shanghai China.
Jinxin LiuLaboratory of Gastrointestinal Microbiology, College of Animal Science & Technology Nanjing Agricultural University Nanjing China.ORCID 0000-0002-5302-866X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The infant gut microbiome is increasingly recognized as a reservoir of antibiotic resistance genes, yet the assembly of gut resistome in infants and its influencing factors remain largely unknown. We characterized resistome in 4132 metagenomes from 963 infants in six countries and 4285 resistance genes were observed. The inherent resistome pattern of healthy infants (

Indexed as

ageantimicrobial resistance genescarbohydrate metabolismdietinfant gut resistomemetagenomics

Identifiers

PMID38882494
PMCPMC11170968

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.