Evidence map›Paper›PMID 38882464›Full record

ArticleResearch and practice in thrombosis and haemostasis2024

A real-time prognostic model for venous thromboembolic events among hospitalized adults.

Benjamin F Tillman, Henry J Domenico, Ryan P Moore, Daniel W Byrne, Colleen T Morton, Amanda S Mixon, Benjamin French

Registry-linked trialAbstract read
In one paragraph

Article in Research and practice in thrombosis and haemostasis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06939803 (AI-driven Clinical Decision Support to Reduce Hospital-Acquired Venous Thromboembolism), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06939803 narecruitingnot on this mapstarted 2025, after this paper: background citation

AI-driven Clinical Decision Support to Reduce Hospital-Acquired Venous Thromboembolism

TypeinterventionalSponsorVanderbilt University Medical CenterRan2025 to 2027Enrolled2,236ConditionsVenothromboembolismArmsRisk model-driven CDS
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Benjamin F TillmanDivision of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Henry J DomenicoDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Ryan P MooreDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Daniel W ByrneDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Colleen T MortonDivision of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Amanda S MixonDepartment of Medicine, Center for Quality Aging, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Benjamin FrenchDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hospital-acquired venous thromboembolism (HA-VTE) is a leading cause of morbidity and mortality among hospitalized adults. Guidelines recommend use of a risk-prediction model to estimate HA-VTE risk for individual patients. Extant models do not perform well for broad patient populations and are not conducive to automation in clinical practice. Objectives: To develop an automated, real-time prognostic model for venous thromboembolism during hospitalization among all adult inpatients using readily available data from the electronic health record. Methods: The derivation cohort included inpatient hospitalizations ("encounters") for patients ≥16 years old at Vanderbilt University Medical Center between 2018 and 2020 ( Results: There were 1187 HA-VTEs in the derivation cohort (9.0 per 1000 encounters) and 864 in the validation cohort (13.8 per 1000 encounters). The prognostic model included 25 variables, with placement of a central line among the most important predictors. Prediction performance of the model was excellent ( Conclusion: This fully automated prognostic model uses readily available data from the electronic health record, exhibits superior prediction performance compared with existing models, and generates granular risk stratification in the form of a predicted probability of HA-VTE for each patient.

Indexed as

inpatientsprognosisrisksafetyvenous thromboembolism

Identifiers

PMID38882464
PMCPMC11179067

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.