Evidence map›Paper›PMID 38882320›Full record

ArticleHeliyon2024

Limosilactobacillus fermentum TY-S11 ameliorates hypercholesterolemia via promoting cholesterol excretion and regulating gut microbiota in high-cholesterol diet-fed apolipoprotein E-deficient mice.

Yadan Deng, Jing Wang, Ran Wang, Yuying Wang, Xi Shu, Pengjie Wang, Chong Chen, Feng Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yadan DengKey Laboratory of Conservation, Exploration and Utilization of Southwest Characteristic Bacterial Germplasm Resources, Chongqing Tianyou Dairy Co., Ltd., Chongqing, 401120, China.
Jing WangKey Laboratory of Conservation, Exploration and Utilization of Southwest Characteristic Bacterial Germplasm Resources, Chongqing Tianyou Dairy Co., Ltd., Chongqing, 401120, China.
Ran WangDepartment of Nutrition and Health, Key Laboratory of Functional Dairy, Co-constructed by Ministry of Education and Beijing Government, China Agricultural University, Beijing, 100190, China.
Yuying WangKey Laboratory of Conservation, Exploration and Utilization of Southwest Characteristic Bacterial Germplasm Resources, Chongqing Tianyou Dairy Co., Ltd., Chongqing, 401120, China.
Xi ShuKey Laboratory of Conservation, Exploration and Utilization of Southwest Characteristic Bacterial Germplasm Resources, Chongqing Tianyou Dairy Co., Ltd., Chongqing, 401120, China.
Pengjie WangDepartment of Nutrition and Health, Key Laboratory of Functional Dairy, Co-constructed by Ministry of Education and Beijing Government, China Agricultural University, Beijing, 100190, China.
Chong ChenKey Laboratory of Conservation, Exploration and Utilization of Southwest Characteristic Bacterial Germplasm Resources, Chongqing Tianyou Dairy Co., Ltd., Chongqing, 401120, China.
Feng ZhangKey Laboratory of Conservation, Exploration and Utilization of Southwest Characteristic Bacterial Germplasm Resources, Chongqing Tianyou Dairy Co., Ltd., Chongqing, 401120, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypercholesterolemia is a metabolic disease characterized by elevated cholesterol level in the blood, which is a risk factor for many diseases. Probiotic intervention may be one of the ways to improve hypercholesterolemia. In this study, three strains with better cholesterol removal ability were selected from 60 strains of lactic acid bacteria, and were orally administered to apolipoprotein E-deficient mice on a high-cholesterol diet. Among the three strains, only

Indexed as

Cholesterol excretionGut microbiotaHypercholesterolemiaLactic acid bacteriaShort-chain fatty acids

Identifiers

PMID38882320
PMCPMC11180314

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.