Evidence map›Paper›PMID 38882318›Full record

ReviewHeliyon2024

Revealing the mechanism and efficacy of natural products on treating the asthma: Current insights from traditional medicine to modern drug discovery.

Dionysius Subali, Rudy Kurniawan, Reggie Surya, In-Seon Lee, Sanghyun Chung, Seok-Jae Ko, Myunghan Moon, Jinwon Choi, Moon Nyeo Park, Nurpudji Astuti Taslim and 4 more

Abstract readReview
In one paragraph

Review in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Frontiers in pharmacology · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Food science and biotechnology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Dionysius SubaliDepartment of Biotechnology, Faculty of Biotechnology, Atma Jaya Catholic University of Indonesia, Jakarta, 12930, Indonesia.
Rudy KurniawanDiabetes Connection Care, Eka Hospital Bumi Serpong Damai, Tangerang, 15321, Indonesia.
Reggie SuryaDepartment of Food Technology, Faculty of Engineering, Bina Nusantara University, Jakarta, 11480, Indonesia.
In-Seon LeeCollege of Korean Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea.
Sanghyun ChungDepartment of Pathology, College of Korean Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea.
Seok-Jae KoDepartment of Gastroenterology, College of Korean Medicine, Kyung Hee University, Seoul, 05253, Republic of Korea.
Myunghan MoonDepartment of Pathology, College of Korean Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea.
Jinwon ChoiDepartment of Pathology, College of Korean Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea.
Moon Nyeo ParkDepartment of Pathology, College of Korean Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea.
Nurpudji Astuti TaslimDivision of Clinical Nutrition, Department of Nutrition, Faculty of Medicine, Hasanuddin University, Makassar, 90245, Indonesia.
Hardinsyah HardinsyahDivision of Applied Nutrition, Department of Community Nutrition, Faculty of Human Ecology, IPB University, Bogor, 16680, Indonesia.
Fahrul NurkolisDepartment of Biological Sciences, Faculty of Sciences and Technology, State Islamic University of Sunan Kalijaga (UIN Sunan Kalijaga), Yogyakarta, 55281, Indonesia.
Bonglee KimDepartment of Pathology, College of Korean Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea.
Kwan-Il KimDivision of Allergy, Immune and Respiratory System, Department of Internal Medicine, College of Korean Medicine, Kyung Hee University Medical Center, Kyung Hee University, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma remains a significant global health challenge, demanding innovative approaches to treatment. Traditional medicine has a rich history of using natural products to alleviate asthmatic symptoms. However, transitioning from these traditional remedies to modern drug discovery approaches has provided fresh insights into the mechanisms and effectiveness of these natural products. This study provides our comprehensive review, which examines the current state of knowledge in the treatment of asthma. It delves into the mechanisms through which natural products ameliorate asthma symptoms, and it discusses their potential in the development of novel therapeutic interventions. Our analysis reveals that natural products, traditionally employed for asthma relief, exhibit diverse mechanisms of action. These include anti-inflammatory, bronchodilatory, immunomodulatory effects, and reducing gene expression. In the context of modern drug discovery, these natural compounds serve as valuable candidates for the development of novel asthma therapies. The transition from traditional remedies to modern drug discovery represents a promising avenue for asthma treatment. Our review highlights the substantial efficacy of natural products in managing asthma symptoms, underpinned by well-defined mechanisms of action. By bridging the gap between traditional and contemporary approaches, we contribute to the growing body of knowledge in the field, emphasizing the potential of natural products in shaping the future of asthma therapy.

Indexed as

Anti-inflammatoryAsthmaEfficacyHerbal medicinesImmunomodulatoryModern drugNatural productTraditional medicine

Identifiers

PMID38882318
PMCPMC11176852

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.