Evidence map›Paper›PMID 38882182›Full record

ArticleAmerican journal of medicine open2024

Collective Weakness and Fluidity in Weakness Status Associated With Basic Self-Care Limitations in Older Americans.

Ryan McGrath, Brenda M McGrath, Soham Al Snih, Peggy M Cawthon, Brian C Clark, Halli Heimbuch, Mark D Peterson, Yeong Rhee

Abstract read
In one paragraph

Article in American journal of medicine open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. 5-HTGeroScience · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ryan McGrathHealthy Aging North Dakota (HAND), North Dakota State University, Fargo, ND, USA.
Brenda M McGrathOCHIN Inc. Portland, OR, USA.
Soham Al SnihDepartment of Population Health and Health Disparities, University of Texas Medical Branch, Galveston, TX, USA.
Peggy M CawthonCalifornia Pacific Medical Center Research Institute, San Francisco, CA, USA.
Brian C ClarkOhio Musculoskeletal and Neurological Institute, Ohio University, Athens, OH, USA.
Halli HeimbuchHealthy Aging North Dakota (HAND), North Dakota State University, Fargo, ND, USA.
Mark D PetersonDepartment of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI, USA.
Yeong RheeDepartment of Health, Nutrition, and Exercise Sciences, North Dakota State University, Fargo, ND, USA.

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Neuronal mechanisms involved in aging and ADR01AG067758 · NIA · OHIO UNIVERSITY ATHENS · PI ARNOLD, WILLIAM DAVID, CLARK, BRIAN C · 2021 to 2025
$4.1M
GRip Assessment for Protocol Enhancements (GRAPE) in Older AdultsR15AG072348 · NIA · NORTH DAKOTA STATE UNIVERSITY · PI MCGRATH, RYAN · 2022 to 2025
$838k
NIA NIH HHS R01 AG067758NIA NIH HHS R15 AG072348NIA NIH HHS U01 AG009740
6 · The paper itself

Abstract

Aims: To examine the associations of 1) absolute and normalized weakness cut-points, 2) collective weakness categories, and 3) changes in weakness status on future activities of daily living (ADL) limitations in older Americans. Methods: The analytic sample included 11,656 participants aged ≥65-years from the 2006-2018 waves of the Health and Retirement Study. ADL were self-reported. A handgrip dynamometer measured handgrip strength (HGS). Males were classified as weak if their HGS was <35.5-kg (absolute), <0.45-kg/kg (body mass normalized), or <1.05-kg/kg/m Results: Older Americans below absolute and normalized weakness cut-points had greater future ADL limitations odds: 1.34 (95% confidence interval (CI): 1.22-1.47) for absolute, 1.36 (CI: 1.24-1.50) for BMI normalized, and 1.56 (CI: 1.41-1.73) for body mass normalized. Persons below 1, 2, or 3 cut-points had 1.36 (CI: 1.19-1.55), 1.60 (CI: 1.41-1.80), and 1.70 (CI: 1.50-1.92) greater odds for future ADL limitations, respectively. Those in each changing weakness classification had greater future ADL limitation odds: 1.28 (CI: 1.01-1.62) for onset, 1.53 (CI: 1.22-1.92) for persistent, 1.72 (CI: 1.36-2.19) for progressive, and 1.34 (CI: 1.08-1.66) for recovery. Conclusions: The presence of weakness, regardless of cut-point and change in status over time, was associated with greater odds for future ADL limitations.

Indexed as

AgingGeriatric AssessmentLongevityMuscle StrengthMuscle Strength Dynamometer

Identifiers

PMID38882182
PMCPMC11178285

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.