Evidence map›Paper›PMID 38882127›Full record

ArticleACS omega2024

Design and Synthesis of Quinoxaline Hybrids as Modulators of HIF-1a, VEGF, and p21 for Halting Colorectal Cancer.

Mohammed Salah Ayoup, Ahmed R Rabee, Hamida Abdel-Hamid, Adel Amer, Marwa M Abu-Serie, Samah Ashraf, Doaa A Ghareeb, Rabab S Ibrahim, Mohammed B Hawsawi, Amr Negm and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Design and Pictet-Spengler enabled synthesis of carboxamide-substituted imidazo[1,2-Journal of enzyme inhibition and medicinal chemistry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mohammed Salah AyoupDepartment of Chemistry, College of Science, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID https://orcid.org/0000-0001-6715-5478
Ahmed R RabeeChemistry Department, Faculty of Science, Alexandria University, P.O. Box 426, Alexandria 21321, Egypt.
Hamida Abdel-HamidChemistry Department, Faculty of Science, Alexandria University, P.O. Box 426, Alexandria 21321, Egypt.
Adel AmerChemistry Department, Faculty of Science, Alexandria University, P.O. Box 426, Alexandria 21321, Egypt.
Marwa M Abu-SerieMedical Biotechnology Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), New Borg El Arab, Alexandria 21934, Egypt.
Samah AshrafBio-screening and Preclinical Trial Lab, Biochemistry Department, Faculty of Science, Alexandria University, 21511 Alexandria, Egypt.
Doaa A GhareebBio-screening and Preclinical Trial Lab, Biochemistry Department, Faculty of Science, Alexandria University, 21511 Alexandria, Egypt.ORCID https://orcid.org/0000-0003-3327-4377
Rabab S IbrahimDepartment of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo 11754, Egypt.
Mohammed B HawsawiDepartment of Chemistry, Faculty of Science, Umm Al-Qura University, Al Taif Road, Makkah 24382, Saudi Arabia.ORCID https://orcid.org/0000-0003-1527-5560
Amr NegmDepartment of Chemistry, College of Science, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID https://orcid.org/0000-0001-9801-3261
Magda M F IsmailDepartment of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo 11754, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A library of 16 3-benzyl-

Identifiers

PMID38882127
PMCPMC11170630

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.