Evidence map›Paper›PMID 38881902›Full record

ReviewFrontiers in immunology2024

From mechanism to therapy: the journey of CD24 in cancer.

Kai Zhao, Caifeng Wu, Xiangjun Li, Mengchao Niu, Dan Wu, Xiaofeng Cui, Hai Zhao

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Targeting CD24 Activates Macrophages to Reduce Tumor Burden in Preclinical Models of Solid Tumors.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kai ZhaoDepartment of Neurosurgery, The Affiliated Hospital of Qingdao University, Qingdao, China.
Caifeng WuDepartment of Hand and Foot, The Affiliated Hospital of Qingdao University, Qingdao, China.
Xiangjun LiDepartment of Breast Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.
Mengchao NiuDepartment of Operation Room, The Affiliated Hospital of Qingdao University, Qingdao, China.
Dan WuDepartment of Neurosurgery, The Affiliated Hospital of Qingdao University, Qingdao, China.
Xiaofeng CuiDepartment of Neurosurgery, The Affiliated Hospital of Qingdao University, Qingdao, China.
Hai ZhaoDepartment of Neurosurgery, The Affiliated Hospital of Qingdao University, Qingdao, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD24 is a glycosylphosphatidylinositol-anchored protein that is expressed in a wide range of tissues and cell types. It is involved in a variety of physiological and pathological processes, including cell adhesion, migration, differentiation, and apoptosis. Additionally, CD24 has been studied extensively in the context of cancer, where it has been found to play a role in tumor growth, invasion, and metastasis. In recent years, there has been growing interest in CD24 as a potential therapeutic target for cancer treatment. This review summarizes the current knowledge of CD24, including its structure, function, and its role in cancer. Finally, we provide insights into potential clinical application of CD24 and discuss possible approaches for the development of targeted cancer therapies.

Indexed as

CD24 AntigenNeoplasmsAnimalsHumansMolecular Targeted TherapyCD24 AntigenCD24 protein, humancancerCD24innate checkpointphagocytosistherapeutic target

Identifiers

PMID38881902
PMCPMC11176514

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.