Evidence map›Paper›PMID 38881801›Full record

SynthesisTransplant international : official journal of the European Society for Organ Transplantation2024

Simultaneous Heart and Kidney Transplantation: A Systematic Review and Proportional Meta-Analysis of Its Characteristics and Long-Term Variables.

Natália Zaneti Sampaio, Matheus Daniel Faleiro, Laynara Vitória da Silva Vieira, Gabriele Eckerdt Lech, Sofia Wagemaker Viana, Clara Pereira Oliveira Tavares, Adela D Mattiazzi, George W Burke

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Transplant international : official journal of the European Society for Organ Transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Tolerogenic Therapies in Cardiac Transplantation.International journal of molecular sciences · 2025
    Review
  6. 2024: A Year in Review.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Natália Zaneti SampaioUniversity of Araraquara, Araraquara, Brazil.
Matheus Daniel FaleiroFederal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Laynara Vitória da Silva VieiraFederal University of Piauí, Teresina, Piauí, Brazil.
Gabriele Eckerdt LechPontifical Catholic University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
Sofia Wagemaker VianaKursk State Medical University, Kursk, Kursk Oblast, Russia.
Clara Pereira Oliveira TavaresSalvador University, Salvador, Bahia, Brazil.
Adela D MattiazziLeonard M. Miller School of Medicine, University of Miami, Miami, FL, United States.
George W BurkeLeonard M. Miller School of Medicine, University of Miami, Miami, FL, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with end-stage heart disease who undergo a heart transplant frequently have simultaneous kidney insufficiency, therefore simultaneous heart and kidney transplantation is an option and it is necessary to understand its characteristics and long-term variables. The recipient characteristics and operative and long-term variables were assessed in a meta-analysis. A total of 781 studies were screened, and 33 were thoroughly reviewed. 15 retrospective cohort studies and 376 patients were included. The recipient's mean age was 51.1 years (95% CI 48.52-53.67) and 84% (95% CI 80-87) were male. 71% (95% CI 59-83) of the recipients were dialysis dependent. The most common indication was ischemic cardiomyopathy [47% (95% CI 41-53)] and cardiorenal syndrome [22% (95% CI 9-35)]. Also, 33% (95% CI 20-46) of the patients presented with delayed graft function. During the mean follow-up period of 67.49 months (95% CI 45.64-89.33), simultaneous rejection episodes of both organ allografts were described in 5 cases only. Overall survival was 95% (95% CI 88-100) at 30 days, 81% (95% CI 76-86) at 1 year, 79% (95% CI 71-87) at 3, and 71% (95% CI 59-83) at 5 years. Simultaneous heart and kidney transplantation is an important option for concurrent cardiac and renal dysfunction and has acceptable rejection and survival rates.

Indexed as

Graft RejectionGraft SurvivalHeart TransplantationKidney TransplantationCardio-Renal SyndromeDelayed Graft FunctionFemaleHeart FailureHumansKidney Failure, ChronicMaleMiddle AgedRetrospective StudiesTreatment Outcomeheart transplantationkidney transplantationmultiorgan transplantsimultaneous heart and kidney transplantationtransplant

Identifiers

PMID38881801
PMCPMC11176494

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.