Evidence map›Paper›PMID 38881638›Full record

ArticleJournal of dental research, dental clinics, dental prospects2024

Antibacterial effects of children's and adults' toothpastes containing different amounts of fluoride: An in vitro study.

Arthit Klaophimai, Orada Tosrisawatkasem, Sivaporn Horsophonphong

Abstract read
In one paragraph

Article in Journal of dental research, dental clinics, dental prospects, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Arthit KlaophimaiDepartment of Oral Microbiology, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0009-0007-7174-3855
Orada TosrisawatkasemDepartment of Oral Microbiology, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.
Sivaporn HorsophonphongDepartment of Pediatric Dentistry, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0002-3315-2989

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In recent years, fluoride concentrations in toothpaste for children and adults have increased. However, the effects of different concentrations on bacterial activity have rarely been compared. We aimed to investigate and compare the antibacterial activity of children's and adults' toothpaste containing 500, 1000‒1100, and 1450‒1500 ppm fluoride. Methods: Three strains of bacteria ( Results: No difference in the inhibition zone was observed for different fluoride concentrations. However, there were significant differences between toothpastes for children and adults, with higher inhibition zones for adults' toothpastes. Most toothpastes for adults contained SLS, which was associated with antibacterial activity. Conclusion: Fluoride concentrations ranging from 500 to 1500 ppm did not affect bacterial growth. The antibacterial activity of toothpastes for adults was significantly higher than that of toothpastes for children, which was mainly attributed to the SLS usually added to adult formulations.

Indexed as

AdultsAntibacterialChildrenFluorideLactobacillus caseiStreptococcus mutansStreptococcus salivariusToothpaste

Identifiers

PMID38881638
PMCPMC11179140

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.