Evidence map›Paper›PMID 38881558›Full record

ArticleCurrent research in structural biology2024

Evaluating therapeutic potential of AYUSH-64 constituents against omicron variant of SARS-CoV-2 using ensemble docking and simulations.

Vinod Jani, Shruti Koulgi, Mallikarjunachari V N Uppuladinne, Saket Ram Thrigulla, Manohar Gundeti, Goli Penchala Prasad, Sanjaya Kumar, Srikanth Narayanam, Uddhavesh Sonavane, Rajendra Joshi

Abstract read
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In one paragraph

Article in Current research in structural biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Vinod JaniHigh Performance Computing - Medical and Bioinformatics Applications Group, Centre for Development of Advanced Computing (C-DAC), Panchawati, Pashan, 411 008, Pune, India.
Shruti KoulgiHigh Performance Computing - Medical and Bioinformatics Applications Group, Centre for Development of Advanced Computing (C-DAC), Panchawati, Pashan, 411 008, Pune, India.
Mallikarjunachari V N UppuladinneHigh Performance Computing - Medical and Bioinformatics Applications Group, Centre for Development of Advanced Computing (C-DAC), Panchawati, Pashan, 411 008, Pune, India.
Saket Ram ThrigullaCentral Council for Research in Ayurvedic Sciences (CCRAS)-National Institute of Indian Medical Heritage, 500036, Hyderabad, India.
Manohar GundetiCentral Council for Research in Ayurvedic Sciences (CCRAS)-Central Ayurveda Research Institute, 400018, Mumbai, India.
Goli Penchala PrasadCentral Council for Research in Ayurvedic Sciences (CCRAS)-National Institute of Indian Medical Heritage, 500036, Hyderabad, India.
Sanjaya KumarCentral Council for Research in Ayurvedic Sciences (CCRAS), 110058, New Delhi, India.
Srikanth NarayanamCentral Council for Research in Ayurvedic Sciences (CCRAS), 110058, New Delhi, India.
Uddhavesh SonavaneHigh Performance Computing - Medical and Bioinformatics Applications Group, Centre for Development of Advanced Computing (C-DAC), Panchawati, Pashan, 411 008, Pune, India.
Rajendra JoshiHigh Performance Computing - Medical and Bioinformatics Applications Group, Centre for Development of Advanced Computing (C-DAC), Panchawati, Pashan, 411 008, Pune, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic in the later phase showed the presence of the B.1.1.529 variant of the SARS-CoV-2 designated as Omicron. AYUSH-64 a poly herbal drug developed by Central Council for Research in Ayurvedic Sciences (CCRAS) has been recommended by Ministry of Ayush in asymptomatic, mild to moderate COVID-19 patients. One of the earlier,

Indexed as

AyurvedaAyush64Ensemble dockingMD simulationsPhytochemicals

Identifiers

PMID38881558
PMCPMC11179622

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.