ArticleAlcohol and alcoholism (Oxford, Oxfordshire)2024
Relationship between alcohol intake based on daily smartphone-reported consumption and PEth concentrations in healthy volunteers.
Article in Alcohol and alcoholism (Oxford, Oxfordshire), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Reference values for the alcohol biomarker phosphatidylethanol (PEth) in the Belgian population: Insights from a nationwide microsampling study.Drug and alcohol dependence reports · 2026Article
- PEth Cut-Off Thresholds for Hazardous Alcohol Consumption Based on a Drinking Study.Drug testing and analysis · 2026Article
- Impact of Sex, Age, Body Composition and Kidney Function on the Relationship Between Self-Reported Alcohol Consumption and Phosphatidylethanol-Data From the HUNT Study.Basic & clinical pharmacology & toxicology · 2025Article
- Clinical trial design, biomarkers and end points in metabolic and alcohol-related liver disease.Nature reviews. Gastroenterology & hepatology · 2025Review
- Evaluating a drink-counting and a breathalyzer-coupled app for monitoring alcohol use: A comparison with timeline followback and peth biomarker.Addictive behaviors reports · 2025Article
- MetALD: New Perspectives on an Old Overlooked Disease.Liver international : official journal of the International Association for the Study of the Liver · 2025Review
- Article
- Assessing alcohol consumption across phosphatidylethanol levels using HDL-cholesterol as a predictor.Alcohol and alcoholism (Oxford, Oxfordshire) · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
aimsTo investigate the association between alcohol consumption registered daily with a digital smartphone-based diary and concentration of phosphatidylethanol (PEth) 16:0/18:1 in a population without a known alcohol use disorder (AUD), and evaluate whether prospective registration of alcohol consumption is better than retrospective registration and if the association between alcohol intake and PEth was affected by sex or body mass index (BMI).
methodsA total of 41 women and 21 men without AUD-diagnosis registered their alcohol consumption prospectively with a digital diary for 14 days, and retrospectively with the Timeline Followback method in the same time interval. PEth was measured before and after the registration period.
resultsThe correlation between alcohol consumption and PEth varied from 0.65 to 0.87. It did not depend significantly on the reporting method, and was not influenced by sex or BMI. Based on the regression coefficient, a reduction of alcohol consumption by two alcohol units (26 g of pure ethanol) per day would lead to a reduction of the PEth concentration of about 0.1 μmol/l, and vice versa.
conclusionsThere was a good correlation between PEth concentration and alcohol consumption, both when alcohol consumption was reported prospectively and retrospectively. The preferred cut-off for PEth should be adjusted to the level of alcohol consumption considered harmful and a purposeful trade-off between sensitivity and specificity. In order to identify persons with a daily alcohol consumption of more than two or three units of alcohol with a sensitivity of 80% or 90%, we suggest a cut-off of around 0.1 μmol/l.
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