ArticleHypertension (Dallas, Tex. : 1979)2024
Chronic Hypertension During Pregnancy: Prevalence and Treatment in the United States, 2008-2021.
Article in Hypertension (Dallas, Tex. : 1979), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24 citing papers in PubMed.
- Article
- Long-term cardiovascular risks in patients with hypertensive disorders of pregnancy treated with nifedipine or labetalol.International journal of cardiology. Cardiovascular risk and prevention · 2026Article
- Maternal Hypertension, Diabetes, and Preterm Birth Risk Among Infants With Trisomy 21 in Texas, 1999-2018.Birth defects research · 2026Article
- Gestational ages-specific blood pressure patterns and risk of adverse pregnancy outcomes in women with chronic hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- A First-Trimester Serum Proteomic Signature for Early Prediction of Preeclampsia: Integrated Untargeted and Targeted Mass Spectrometry with Machine Learning.Life (Basel, Switzerland) · 2026Article
- "Actionable" risk for preterm birth: patterns and prediction in California singleton births 2016-2020.BMC pregnancy and childbirth · 2026Article
- Antihypertensive drug use for hypertensive disorders of pregnancy in hospitals across nine Chinese cities: a real-world data study.BMC pregnancy and childbirth · 2026Article
- A comparative analysis of blood pressure categorization using 24-hour ambulatory blood pressure monitoring in young women with presumed chronic hypertension with and without a history of pregnancy.AJOG global reports · 2026Article
- Food desert residence and prenatal diet quality.Pregnancy (Hoboken, N.J.) · 2026Article
- Evaluation of Home Blood Pressure Monitoring for Patients with Hypertensive Disorders of Pregnancy: A Rapid Review.Healthcare (Basel, Switzerland) · 2026Review
- A 'Standard of Care PLUS' Model for Preterm Birth Prevention: Integrating Nutrient and Gene Variant Analysis with Targeted Interventions.Journal of personalized medicine · 2026Article
- Use and Out-of-Pocket Costs of Antenatal Fetal Surveillance for Patients With Chronic Conditions.O&G open · 2026Article
- Machine Learning and Blood-Targeted Proteomics Enable Early Prediction and Etiological Discrimination of Hypertensive Pregnancy Disorders.International journal of molecular sciences · 2026Article
- NIT_CH: A study protocol for evaluating the effect of inorganic nitrate capsules in chronic hypertensive pregnancies - a triple-blind placebo-controlled randomized trial.BMC pregnancy and childbirth · 2026Article
- Hypertensive disorders of pregnancy (HDP) mortality in the United States: a CDC WONDER population analysis, 1999-2023.Frontiers in reproductive health · 2026Article
- Comparative Effectiveness and Safety of Labetalol Versus Nifedipine for Treatment of Chronic Hypertension During Pregnancy.JACC. Advances · 2025Article
- Hospital birth volume and rurality: Associations with pregnancy outcomes among individuals with chronic hypertension.Pregnancy (Hoboken, N.J.) · 2025Article
- Utility of the US Preventive Services Task Force for Preeclampsia Risk Assessment and Aspirin Prophylaxis.JAMA network open · 2025Observational
- History of hypertensive disorders of pregnancy and risk of Alzheimer's disease and vascular dementia.Frontiers in neuroendocrinology · 2025Review
- Global temporal trends in maternal hypertensive disorders incidence and mortality from 1990 to 2021 based on the global burden of disease study.Scientific reports · 2025Article
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Abstract
backgroundTreatment of chronic hypertension during pregnancy has been shown to reduce the risk of adverse perinatal outcomes. In this study, we examined the prevalence and treatment of chronic hypertension during pregnancy and assessed changes in these outcomes following the release of the updated 2017 hypertension guidelines of the American College of Cardiology and American Heart Association.
methodsWe analyzed the Merative
resultsThe prevalence of chronic hypertension steadily increased from 1.8% to 3.7% among 1 900 196 pregnancies between 2008 and 2021. Antihypertensive medication use among pregnant individuals with chronic hypertension was relatively stable (57%-60%) over the study period. The proportion of pregnant individuals with chronic hypertension treated with methyldopa or hydrochlorothiazide decreased (from 29% to 2% and from 11% to 5%, respectively), while the proportion treated with labetalol or nifedipine increased (from 19% to 42% and from 9% to 17%, respectively). The prevalence or treatment of chronic hypertension during pregnancy did not change following the 2017 American College of Cardiology and American Heart Association hypertension guidelines.
conclusionsThe prevalence of chronic hypertension during pregnancy doubled between 2008 and 2021 in a nationwide cohort of individuals with commercial insurance. Labetalol replaced methyldopa as the most commonly used antihypertensive during pregnancy. However, only about 60% of individuals with chronic hypertension in pregnancy were treated with antihypertensive medications.
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