Evidence map›Paper›PMID 38881031›Full record

ReviewCancer control : journal of the Moffitt Cancer Center

A Review: Genetic Mutations as a Key to Unlocking Drug Resistance in Cervical Cancer.

Carla Eksteen, Johann Riedemann, Atarah M Rass, Manisha du Plessis, Matthys H Botha, Frederick H van der Merwe, Anna-Mart Engelbrecht

Abstract readReview
In one paragraph

Review in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
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  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carla EksteenCancerCare, Cape Gate Oncology Centre, Cape Town, South Africa.ORCID 0000-0002-2052-3330
Johann RiedemannCancerCare, Cape Gate Oncology Centre, Cape Town, South Africa.
Atarah M RassDepartment of Physiological Sciences, Faculty of Science, University of Stellenbosch, Stellenbosch, South Africa.
Manisha du PlessisDepartment of Physiological Sciences, Faculty of Science, University of Stellenbosch, Stellenbosch, South Africa.
Matthys H BothaDepartment of Obstetrics and Gynecology, Stellenbosch University, Stellenbosch, South Africa.
Frederick H van der MerweDepartment of Obstetrics and Gynecology, Stellenbosch University, Stellenbosch, South Africa.
Anna-Mart EngelbrechtDepartment of Physiological Sciences, Faculty of Science, University of Stellenbosch, Stellenbosch, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer is the fourth most common cancer in women. Advanced stage and metastatic disease are often associated with poor clinical outcomes. This substantiates the absolute necessity for high-throughput diagnostic and treatment platforms that are patient and tumour specific. Cervical cancer treatment constitutes multimodal intervention. Systemic treatments such as chemotherapy and/or focal radiotherapy are typically applied as neoadjuvant and/or adjuvant strategies. Cisplatin constitutes an integral part of standard cervical cancer treatment approaches. However, despite initial patient response,

Indexed as

Drug Resistance, NeoplasmMutationUterine Cervical NeoplasmsAntineoplastic AgentsFemaleHumansAntineoplastic Agentscervical cancercisplatingenetic mutationsprecision oncologytreatment resistance

Identifiers

PMID38881031
PMCPMC11181891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.