ArticleDiabetology & metabolic syndrome2024
J-shaped relationship between stress hyperglycemia ratio and 90-day and 180-day mortality in patients with a first diagnosis of acute myocardial infarction: analysis of the MIMIC-IV database.
Article in Diabetology & metabolic syndrome, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Stress hyperglycemia ratio in coronary artery disease: a systematic review and meta-analysis of severity and prognosis.Cardiovascular diabetology · 2026Pooled it
- Predictive performance of stress hyperglycemia ratio for poor prognosis in critically ill patients: a systematic review and dose-response meta-analysis.European journal of medical research · 2025Pooled it
- Prognostic value of stress hyperglycemia ratio in critically Ill patients with acute kidney injury: a machine learning-driven retrospective cohort analysis.Health information science and systems · 2026Article
- Association of early blood glucose metrics with short- and long-term prognosis in acute myocardial infarction patients: a retrospective cohort study.BMC cardiovascular disorders · 2026Article
- Association between stress hyperglycemia ratio and all-cause mortality in neurocritical patients.Scientific reports · 2026Article
- Stress hyperglycemia ratio in risk stratification and treatment optimization for patients on invasive mechanical ventilation: a secondary analysis of the MIMIC-IV database.BMC infectious diseases · 2026Article
- Impact of Stress Hyperglycemia Ratio on Adverse Outcomes in Patients With Chronic Thromboembolic Pulmonary Hypertension.Clinical and translational science · 2025Article
- Association between stress hyperglycemia ratio and 28-day all-cause mortality in critically ill atrial fibrillation patients: a retrospective cohort study based on the MIMIC-IV database.Journal of thoracic disease · 2025Article
- Predictive value and robustness of the stress hyperglycemia ratio combined with hypertension for stroke risk: evidence from the CHARLS cohort.Cardiovascular diabetology · 2025Article
- The relationship between admission Braden score and poor prognosis in Sepsis patients: evidence from the MIMIC-III database.BMC infectious diseases · 2025Article
- Impact of stress hyperglycemia ratio on acute kidney injury and mortality in patients with cardiogenic shock: a retrospective analysis.Frontiers in endocrinology · 2025Article
- Association between different hemoglobin glycation index and prognosis in patients with a first diagnosis of acute myocardial infarction: a retrospective study based on the MIMIC-IV database.Frontiers in cardiovascular medicine · 2025Article
- Impact of stress hyperglycemia ratio on incidence of in-hospital cardiogenic shock in patients with ST-elevation myocardial infarction: a prospective, multicenter study.Frontiers in endocrinology · 2025Observational
- The association between stress hyperglycemia ratio and 1-year outcomes in patients with acute myocardial infarction: a retrospective large sample cohort study.Frontiers in endocrinology · 2025Article
- Assessment of stress hyperglycemia ratio to predict mortality in critically ill patients with sepsis: a retrospective cohort study from the MIMIC-IV database.Frontiers in endocrinology · 2025Article
- Article
- Association and predictive ability between significant perioperative cardiovascular adverse events and stress glucose rise in patients undergoing non-cardiac surgery.Cardiovascular diabetology · 2024Article
- Association between stress hyperglycemia ratio and mortality in acute myocardial infarction patients with and without atrial fibrillation: a retrospective cohort study from the MIMIC-IV database.BMC cardiovascular disorders · 2024Article
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Authors and funding
6 authors.
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Abstract
aimsThe Stress Hyperglycemia Ratio (SHR) potently predicts adverse outcomes in patients with cardiovascular and cerebrovascular diseases. However, the relationship between SHR and short-term mortality risk in patients with a first diagnosis of acute myocardial infarction (AMI) remains contentious. This study sought to understand better the relationship between SHR and short-term mortality risk in patients with a first diagnosis of AMI.
methodsWe conducted a cohort study using data from 1961 patients with a first diagnosis of AMI from the MIMIC-IV (version 2.2) database. Patients were divided into three groups based on SHR tertiles. The Cox proportional hazards model and a two-segmented Cox proportional hazards model were used to elucidate the nonlinear relationship between SHR in patients with a first diagnosis of AMI and mortality.
resultsOf the surveyed population, 175 patients (8.92%) died within 90 days, and 210 patients (10.71%) died within 180 days. After multivariate adjustments, elevated SHR levels were significantly and non-linearly associated with a higher risk of 90-day and 180-day mortality in patients with a first diagnosis of AMI, showing a J-shaped correlation with an inflection point at 0.9. Compared to participants with SHR levels below the inflection point, those with higher SHR levels had a fivefold increased risk of 90-day mortality (hazard ratio [HR] 5.74; 95% confidence interval [CI] 3.19, 10.33) and a fourfold increased risk of 180-day mortality (HR 4.56; 95% CI 2.62, 7.95). In the subgroup analysis, patients with pre-diabetes mellitus (pre-DM) and higher SHR levels had increased 90-day (HR 6.90; 95% CI 1.98, 24.02) and 180-day mortality risks (HR 5.30; 95% CI 1.96, 14.27).
conclusionIn patients with a first diagnosis of AMI, there is a J-shaped correlation between SHR and 90-day and 180-day mortality, with an adverse prognostic inflection point of SHR at 0.9.
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