Evidence map›Paper›PMID 38879623›Full record

ArticleNature communications2024

Kinetics and mapping of Ca-driven calmodulin conformations on skeletal and cardiac muscle ryanodine receptors.

Robyn T Rebbeck, Bengt Svensson, Jingyan Zhang, Montserrat Samsó, David D Thomas, Donald M Bers, Razvan L Cornea

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Phosphorylation of RYR1 at SerScience signaling · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Robyn T Rebbeck *Department of Biochemistry, Molecular Biology & Biophysics, University of Minnesota, Minneapolis, MN, USA. rrebbeck@umn.edu.ORCID http://orcid.org/0000-0003-3840-2286
Bengt Svensson *Department of Biochemistry, Molecular Biology & Biophysics, University of Minnesota, Minneapolis, MN, USA.
Jingyan ZhangDepartment of Biochemistry, Molecular Biology & Biophysics, University of Minnesota, Minneapolis, MN, USA.
Montserrat SamsóDepartment of Physiology and Biophysics, Virginia Commonwealth University, Richmond, VA, USA.ORCID http://orcid.org/0000-0002-2788-3283
David D ThomasDepartment of Biochemistry, Molecular Biology & Biophysics, University of Minnesota, Minneapolis, MN, USA.ORCID http://orcid.org/0000-0002-8822-2040
Donald M BersDepartment of Pharmacology, University of California at Davis, Davis, CA, USA.ORCID http://orcid.org/0000-0002-2237-9483
Razvan L CorneaDepartment of Biochemistry, Molecular Biology & Biophysics, University of Minnesota, Minneapolis, MN, USA. corne002@umn.edu.ORCID http://orcid.org/0000-0001-5739-0992

Funding

Pathophysiological Regulation of Cardiac Myocyte RyR ChannelR01HL092097 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Donald M Bers, Robyn T Rebbeck · 2010 to 2026
$9.3M
CaMKII activation and regulation in adult cardiac myocytesR01HL142282 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERS, DONALD M, BOSSUYT, JULIE B · 2018 to 2025
$5.4M
Structural Dynamics of Cardiac Muscle Calcium ATPase RegulationR01HL139065 · NHLBI · UNIVERSITY OF MINNESOTA · PI Robyn T Rebbeck, David D Thomas · 2020 to 2026
$5.2M
Midwest Consortium for High Resolution Cryoelectron MicroscopyU24GM116789 · NIGMS · PURDUE UNIVERSITY · PI BULLITT, ESTHER, DAI, WEI · 2017 to 2021
$3.5M
UVA molecular electron microscopy core for the Mid-Atlantic regionU24GM116790 · NIGMS · UNIVERSITY OF VIRGINIA · PI GALKIN, VITOLD, SAMSO, MONTSERRAT · 2017 to 2021
$2.9M
Skeletal muscle protein structural dynamics and function drive applications to drug discoveryR01AR082533 · NIAMS · UNIVERSITY OF MINNESOTA · PI DAWN A LOWE, Robyn T Rebbeck · 2023 to 2026
$2.5M
RyR architecture and gatekeeping of internal calcium storesR01AR068431 · NIAMS · VIRGINIA COMMONWEALTH UNIVERSITY · PI SAMSO, MONTSERRAT · 2017 to 2021
$2.0M
American Heart Association (American Heart Association, Inc.) 16POST31010019NHLBI NIH HHS R01 HL092097NHLBI NIH HHS R01 HL139065NHLBI NIH HHS R01 HL142282NIAMS NIH HHS R01 AR068431NIAMS NIH HHS R01 AR082533U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL092097U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL139065U.S. Department of Health & Human Services | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) R01AR082533
6 · The paper itself

Abstract

Calmodulin transduces [Ca

Indexed as

CalciumCalmodulinFluorescence Resonance Energy TransferMuscle, SkeletalMyocardiumRyanodine Receptor Calcium Release ChannelAnimalsHumansKineticsProtein BindingProtein ConformationSarcoplasmic ReticulumCalciumCalmodulinRyanodine Receptor Calcium Release Channel

Identifiers

PMID38879623
PMCPMC11180167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.