ArticleJournal of advanced research2024
Associations between specific dietary patterns, gut microbiome composition, and incident subthreshold depression in Chinese young adults.
Article in Journal of advanced research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Gut Microbiota Modulation as a Therapeutic Strategy for Insomnia: A Systematic Review of Nutritional and Botanical Interventions.Biomolecules · 2026Pooled it
- Association between probiotic intervention and sleep quality in the general adult population: a systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- Sex modifies the association of high-altitude hypoxia with poor sleep quality and depression in school-age children and adolescents.Sleep & breathing = Schlaf & Atmung · 2026Article
- Recent Advances in the Brain-Gut Axis in the Development and Progression of Depression.Actas espanolas de psiquiatria · 2026Review
- Gut Microbiota Dysbiosis in Depression: Pathological Correlations, Molecular Pathways, and Therapeutic Interventions.International journal of molecular sciences · 2026Review
- The dual-sensitive period gut-brain crosstalk, neuroinflammation, and the biological roots of adolescent depression.Frontiers in immunology · 2026Review
- Comparison of live birth rates between calorie-restricted diet and metformin prior to ovulation induction therapy in women with polycystic ovary syndrome and overweight/obesity: a protocol for a multicenter, randomized comparative effectiveness trial.Frontiers in public health · 2026Article
- Gut microbiota and metabolic characteristics in subthreshold depression based on multi-omics.Frontiers in psychiatry · 2026Article
- Interactions between upper respiratory microbiota and psychological distress in pulmonary nodule patients: a retrospective nested case-control study based on machine learning and exploratory mediation analysis.International journal of surgery (London, England) · 2025Article
- Heart Rate Variability Biofeedback Alleviates Subthreshold Depression by Reconstructing the Brain-Heart Axis via Habenular Network Functional Connectivity Modulation.CNS neuroscience & therapeutics · 2025Article
- Acupuncture for Major Depressive Disorder: Exploring the Gut Microbiota as a Novel Therapeutic Pathway.Brain and behavior · 2025Article
- Fecal metabolites as early-phase biomarkers and prediction panel for ischemic stroke.BMC microbiology · 2025Article
- The influence of credits and stigmas in volunteering on depression, the modulating effects of volunteer personality and motivation.BMC public health · 2025Article
- Prioritizing psychological relief: fast-absorbing collagen sutures improve parental well-being in pediatric facial trauma care.Frontiers in pediatrics · 2025Article
- Reversal of anxiety-like depression induced by chronic corticosterone by crocin I and surface-enhanced Raman spectroscopy monitoring of plasma metabolites.Frontiers in pharmacology · 2025Article
- Anxiety and Depressive Symptoms Among Kidney Transplant Recipients in Post-COVID-19 China: Prevalence and Risk Factors.Risk management and healthcare policy · 2025Article
- Oral paroxetine improves symptoms and quality of life in refractory irritable bowel syndrome: a retrospective study.American journal of translational research · 2025Article
- Neuroimaging signatures and a deep learning modeling for early diagnosing and predicting non-pharmacological therapy success for subclinical depression comorbid sleep disorders in college students.International journal of clinical and health psychology : IJCHPArticle
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe interplay between influential factors and the incidence of subthreshold depression (SD) in young adults remains poorly understood.
objectivesThis study sought to understand the dietary habits, gut microbiota composition, etc. among individuals with SD in young adults and to investigate their association with SD occurrence.
methodsEmploying a cross-sectional approach, 178 individuals with SD, aged 18-32 years, were matched with 114 healthy counterparts. SD status was evaluated using the Zung Self-rating Depression Scale (SDS), Zung Self-rating Anxiety Scale (SAS), Beck Depression Inventory 2nd version (BDI-II), the 17-item Hamilton Rating Scales of Depression (HAMD-17), and Pittsburgh Sleep Quality Index (PSQI). Metagenomic sequencing was utilized to identify fecal microbial profiles. Dietary patterns were discerned via factor analysis of a 25-item food frequency questionnaire (FFQ). Logistic regression analysis and mediation analysis were performed to explore the potential links between gut microbiota, dietary patterns, and incident SD.
resultsData on dietary habits were available for 292 participants (mean [SD] age, 22.1 [2.9] years; 216 [73.9 %] female). Logistic regression analysis revealed that dietary patterns Ⅰ (odds ratio [OR], 0.34; 95 % CI, 0.15-0.75) and IV (OR, 0.39; 95 % CI, 0.17-0.86 and OR, 0.39; 95 % CI, 0.18-0.84) were associated with reduced risk of SD. Distinct microbial profiles were observed in young adults with SD, marked by increased microbial diversity and taxonomic alterations. Moreover, mediation analysis suggested Veillonella atypica as a potential mediator linking SDS or BDI-II scores with a healthy dietary pattern rich in bean products, coarse grains, nuts, fruits, mushrooms, and potatoes (β = 0.25, 95 % CI: 0.02-0.78 and β = 0.18, 95 % CI: 0.01-0.54).
conclusionsOur findings highlight the complex interplay between dietary patterns, gut microbiota, and the risk of developing SD in young adults, underscoring the potential for dietary interventions and microbiome modulation in mental health promotion.
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