Evidence map›Paper›PMID 38879008›Full record

ArticleThe Journal of biological chemistry2024

Mutation-induced shift of the photosystem II active site reveals insight into conserved water channels.

David A Flesher, Jinchan Liu, Jimin Wang, Christopher J Gisriel, Ke R Yang, Victor S Batista, Richard J Debus, Gary W Brudvig

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Binding of Acetate in the SPlants (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

David A FlesherDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, USA.
Jinchan LiuDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, USA.
Jimin WangDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, USA.
Christopher J GisrielDepartment of Chemistry, Yale University, New Haven, Connecticut, USA.
Ke R YangDepartment of Chemistry, Yale University, New Haven, Connecticut, USA.
Victor S BatistaDepartment of Chemistry, Yale University, New Haven, Connecticut, USA.
Richard J DebusDepartment of Biochemistry, University of California, Riverside, California, USA. Electronic address: richard.debus@ucr.edu.
Gary W BrudvigDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, USA; Department of Chemistry, Yale University, New Haven, Connecticut, USA. Electronic address: gary.brudvig@yale.edu.

Funding

PREDOCTORAL PROGRAM IN BIOPHYSICST32GM008283 · NIGMS · YALE UNIVERSITY · PI XIONG, YONG · 1988 to 2022
$10.5M
Predoctoral Program in BiophysicsT32GM149438 · NIGMS · YALE UNIVERSITY · PI Yong Xiong, Elsa Chui Ying Yan · 2023 to 2026
$2.6M
Photosystem II as a model protein for understanding metalloenzyme active site assemblyK99GM140174 · NIGMS · YALE UNIVERSITY · PI GISRIEL, CHRISTOPHER · 2021 to 2022
$192k
NIGMS NIH HHS K99 GM140174NIGMS NIH HHS T32 GM008283NIGMS NIH HHS T32 GM149438
6 · The paper itself

Abstract

Photosystem II (PSII) is the water-plastoquinone photo-oxidoreductase central to oxygenic photosynthesis. PSII has been extensively studied for its ability to catalyze light-driven water oxidation at a Mn

Indexed as

Catalytic DomainPhotosystem II Protein ComplexWaterCryoelectron MicroscopyManganeseMutationOxidation-ReductionManganesePhotosystem II Protein ComplexWatercryo-EMhydrogen-bond networkmutagenesisoxygen-evolving complexphotosynthesisphotosystem IIquantum mechanics/molecular mechanicswater channel

Identifiers

PMID38879008
PMCPMC11294709

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.