Evidence map›Paper›PMID 38878586›Full record

ArticlePatient education and counseling2024

"A great step in treating cervical cancer": Patient and provider perceptions about cervical cancer therapeutic vaccines.

Ashley Whitmer, Lindsay N Fuzzell, Sylea Lowery, Mariana Arevalo, Julie Rathwell, Brandy Arredondo, Arianna L Mason, Carley Geiss, Anna Giuliano, Susan T Vadaparampil

Abstract read
In one paragraph

Article in Patient education and counseling, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ashley WhitmerNon-Therapeutic Research Office (NTRO), H. Lee Moffitt Cancer Center & Research Institute, Tampa, USA.
Lindsay N FuzzellHealth Outcomes and Behavior (HOB), H. Lee Moffitt Cancer Center & Research Institute, Tampa, USA.
Sylea LoweryMorsani College of Medicine, University of South Florida, Tampa, USA.
Mariana ArevaloHealth Outcomes and Behavior (HOB), H. Lee Moffitt Cancer Center & Research Institute, Tampa, USA.
Julie RathwellCenter for Immunization and Infection Research in Cancer (CIIRC), H. Lee Moffitt Cancer Center & Research Institute, Tampa, USA.
Brandy ArredondoParticipant Research, Interventions, and Measurement (PRISM) Core, H. Lee Moffitt Cancer Center & Research Institute, Tampa, USA.
Arianna L MasonParticipant Research, Interventions, and Measurement (PRISM) Core, H. Lee Moffitt Cancer Center & Research Institute, Tampa, USA.
Carley GeissParticipant Research, Interventions, and Measurement (PRISM) Core, H. Lee Moffitt Cancer Center & Research Institute, Tampa, USA.
Anna GiulianoCenter for Immunization and Infection Research in Cancer (CIIRC), H. Lee Moffitt Cancer Center & Research Institute, Tampa, USA.
Susan T VadaparampilHealth Outcomes and Behavior (HOB), H. Lee Moffitt Cancer Center & Research Institute, Tampa, USA. Electronic address: susan.vadaparampil@moffitt.org.

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI John L. Cleveland · 1998 to 2026
$93.5M
NCI NIH HHS P30 CA076292
6 · The paper itself

Abstract

objectiveThis study explored patients and providers' perspectives on therapeutic vaccines for cervical cancer and assessed barriers and facilitators.

methodsQualitative semi-structured in-depth interviews were conducted with patients who had cervical dysplasia, or a past or current cervical cancer diagnosis and providers who provided care to patients with cervical abnormalities or cervical cancer. Data were analyzed using thematic analysis in NVivo.

resultsA total of 28 in-depth interviews were conducted with patients (N = 15) and providers (N = 13). Participants in both groups expressed enthusiasm for the prospect of a therapeutic vaccine for cervical cancer and were encouraged by less invasive treatment opportunities. Perceived patient barriers included concerns about side effects, eligibility criteria, costs, transportation, and logistical obstacles. Providers echoed these concerns, highlighted additional structural barriers such as racism and limited availability of culturally sensitive educational aids, and underscored the need for provider training on this topic.

conclusionOur results reinforce the need for future multi-level interventions discussing vaccine efficacy, durability, and safety, as well as addressing factors such as awareness, knowledge, and beliefs. PRACTICE IMPLICATIONS: Our findings can contribute to the development of provider and patient-centered tools that promote therapeutic vaccine acceptance.

Indexed as

Health Knowledge, Attitudes, PracticeInterviews as TopicQualitative ResearchUterine Cervical NeoplasmsAdultAgedAttitude of Health PersonnelCancer VaccinesFemaleHealth PersonnelHumansMiddle AgedPapillomavirus InfectionsPapillomavirus VaccinesPatient Acceptance of Health CarePerceptionCancer VaccinesPapillomavirus VaccinesAdultCancer vaccinesCervical cancerFemaleHumansNeoplasmsOncologistsQualitative

Identifiers

PMID38878586
PMCPMC13340439

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.