SynthesisArchives of gynecology and obstetrics2024
Prevention of peritoneal adhesions after gynecological surgery: a systematic review.
Synthesis in Archives of gynecology and obstetrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Feasibility and safety of 4DryFieldArchives of gynecology and obstetrics · 2026Trial
- Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats.Molecular medicine reports · 2026Article
- Surgical management of uterine fibroids.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Review
- Feasibility and Safety of Repeat Robot-Assisted Partial Nephrectomy for Ipsilateral Local Recurrence: A Case Series.International journal of urology : official journal of the Japanese Urological Association · 2026Article
- Prevention of adhesive small bowel obstruction by anti-adhesion barriers: do they really work?Techniques in coloproctology · 2026Review
- Cellular and molecular regulation of fibrotic postoperative abdominal adhesions.American journal of physiology. Cell physiology · 2026Review
- Prevalence, patterns, and associated factors of intraperitoneal adhesions among women undergoing gynaecological laparoscopy at a private endoscopic centre in Southeastern Nigeria.Frontiers in reproductive health · 2026Article
- Efficacy of Intraoperative Adhesion Barrier Use in Laparoscopic Surgery for Endometriosis: A Single-Center Retrospective Study on Long-Term Recurrence and Pelvic Pain.International journal of women's health · 2026Article
- The Effect of Fibrin Sealants on Tubal Reanastomosis: A Comprehensive Review of the Literature.Journal of personalized medicine · 2025Review
- Evaluation Starch-Based Hemostatic Agents "BioSight" as Adhesion Prevention Barrier Tested in an Adhesion Model in Rats.Polymers · 2025Article
- Gynecologic postoperative anti-adhesion barriers: From biomaterials to barrier development.Biomaterials and biosystems · 2025Review
- Biomaterials in Postoperative Adhesion Barriers and Uterine Tissue Engineering.Gels (Basel, Switzerland) · 2025Review
- Adhesion Prevention in Gynecologic Surgery: Guidance and Clinical Experience.Journal of clinical medicine · 2024Review
- Self-Cross-Linked Hyaluronic Acid Gel for Adhesion Prophylaxis in Laparoscopic Deep Endometriosis Removal: Safety Report of a Prospective Pilot Study.Journal of clinical medicine · 2024Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
importanceThe formation of adhesions after gynecological surgery not only has detrimental impacts on those affected, including pain, obstruction, and infertility, but also imposes a high economic burden on healthcare systems worldwide.
objectiveThe aim of this review was to evaluate the adhesion prevention potential of all currently available adhesion barriers for gynecological surgery. EVIDENCE ACQUISITION: We systematically searched MEDLINE and CENTRAL databases for randomized controlled trials (RCTs) on the use of adhesion barriers as compared with peritoneal irrigation or no treatment in gynecological surgery. Only RCTs with second-look surgery to evaluate adhesions in the pelvic/abdominal (but not intrauterine) cavity were included.
resultsWe included 45 RCTs with a total of 4,120 patients examining a total of 10 unique types of barriers in second-look gynecological surgery. While RCTs on oxidized regenerated cellulose (significant improvement in 6 of 14 trials), polyethylene glycol with/without other agents (4/10), hyaluronic acid and hyaluronate + carboxymethylcellulose (7/10), icodextrin (1/3), dextran (0/3), fibrin-containing agents (1/2), expanded polytetrafluoroethylene (1/1), N,O-carboxymethylchitosan (0/1), and modified starch (1/1) overall showed inconsistent findings, results for expanded polytetrafluoroethylene, hyaluronic acid, and modified starch yielded the greatest improvements regarding adhesion reduction at 75%, 0-67%, and 85%, respectively. CONCLUSIONS AND RELEVANCE: Best results for adhesion prevention were reported after applying Gore-Tex Surgical Membrane, hyaluronic acid, and 4DryField
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.