Evidence map›Paper›PMID 38878175›Full record

Trial reportEuropean journal of nuclear medicine and molecular imaging2024

Evaluation of the safety, biodistribution, dosimetry of [

Meixi Liu, Chao Ren, Haiqiong Zhang, Yuwei Zhang, Zhenghai Huang, Ru Jia, Yuejuan Cheng, Chunmei Bai, Qiang Xu, Wenjia Zhu and 1 more

Registry-linked trialAbstract readComparative StudyClinical Trial
PubMed Publisher
In one paragraph

Trial report in European journal of nuclear medicine and molecular imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06056362 (Evaluation of Biodistribution, Dosimetry, Diagnostic Ability, and Safety of Al18F-NOTA-LM3 in Patients With Well-differentiated Neuroendocrine Tumors, and Comparison With 68Ga-DOTATATE and 68Ga-NODAGA-LM3), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06056362 phase1 / phase2recruitingnot on this map

Evaluation of Biodistribution, Dosimetry, Diagnostic Ability, and Safety of Al18F-NOTA-LM3 in Patients With Well-differentiated Neuroendocrine Tumors, and Comparison With 68Ga-DOTATATE and 68Ga-NODAGA-LM3: A Prospective, Single-center, Double-blinded Study

TypeinterventionalSponsorPeking Union Medical College HospitalRan2023 to 2025Enrolled80ConditionsNeuroendocrine TumorsArmsAl18F-NOTA-LM3, 68Ga-DOTATATE, 68Ga-NODAGA-LM3
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Assessment of the diagnostic efficacy and clinical significance of [European journal of nuclear medicine and molecular imaging · 2026
    Trial
  3. Article
  4. Beyond DOTATATE: [European journal of nuclear medicine and molecular imaging · 2026
    Article
  5. Head-to-Head comparison of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Research process of PET tracers for neuroendocrine tumors diagnosis.American journal of nuclear medicine and molecular imaging · 2025
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Meixi Liu *Department of Nuclear Medicine, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
Chao Ren *Department of Nuclear Medicine, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
Haiqiong ZhangDepartment of Nuclear Medicine, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
Yuwei ZhangDepartment of Nuclear Medicine, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
Zhenghai HuangDepartment of Nuclear Medicine, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
Ru JiaDepartment of Gastrointestinal Oncology, The Fifth Medical Center, General Hospital of PLA, Beijing, China.
Yuejuan ChengDepartment of Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, Beijing, 100730, China.
Chunmei BaiDepartment of Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, Beijing, 100730, China.
Qiang XuDepartment of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, Beijing, 100730, China.
Wenjia ZhuDepartment of Nuclear Medicine, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China. zhuwenjia_pumc@163.com.
Li HuoDepartment of Nuclear Medicine, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China. huoli@pumch.cn.ORCID 0000-0003-1216-083X

Funding

CAMS fund for Rare Diseases Research No. 2016ZX310174-4CAMS innovation fund for medical science No. CIFMS-2021-I2M-1-025, CIFMS-2021-I2M-1-002, CIFMS-2021-I2M-1-003China Postdoctoral Science Foundation A1258300National High Level Hospital Clinical Research Funding XH-QN-012K, 2022-PUMCH-D-001, 2022-PUMCH-B-072National Key Research and Development Program of China No. 2016YFC0901500the National Natural Science Foundation of China No. 82071967, 82202218Tsinghua university and PUMCH joint fund No. PTQH201906006
6 · The paper itself

Abstract

purpose

methodsTwenty-one patients with histologically confirmed well-differentiated neuroendocrine tumors (G1 and G2) were prospectively recruited. The first eight patients underwent serial PET scans at 5, 15, 30, 45, 60, and 120 min after [

results[

conclusion[

trial registrationClinicalTrials.gov identifier NCT06056362.

Indexed as

Neuroendocrine TumorsOrganometallic CompoundsAcetatesAdultAgedFemaleHeterocyclic Compounds, 1-RingHumansMaleMiddle AgedPositron Emission Tomography Computed TomographyProspective StudiesRadiometryRadiopharmaceuticalsSafetyTissue Distribution1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane1,4,7-triazacyclononane-N,N',N''-triacetic acidAcetatesgallium Ga 68 dotatateHeterocyclic Compounds, 1-RingOrganometallic CompoundsRadiopharmaceuticals[18F]AlF-NOTA-LM3[68Ga]Ga-DOTATATEAntagonistNeuroendocrine tumorSomatostatin receptor

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.