Evidence map›Paper›PMID 38878135›Full record

ArticleAIDS and behavior2024

Association Between Early Sexual Debut and New HIV Infections Among Adolescents and Young Adults in 11 African Countries.

Jiawei He, Abraham Flaxman, Jeffrey W Imai-Eaton, Aleksandr Aravkin, Peng Zheng, Reed Sorensen, Shachi Mittal, Hmwe H Kyu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiawei HeInstitute for Health Metrics and Evaluation, University of Washington, Seattle, USA.
Abraham FlaxmanInstitute for Health Metrics and Evaluation, University of Washington, Seattle, USA.
Jeffrey W Imai-EatonCenter for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, USA.
Aleksandr AravkinInstitute for Health Metrics and Evaluation, University of Washington, Seattle, USA.
Peng ZhengInstitute for Health Metrics and Evaluation, University of Washington, Seattle, USA.
Reed SorensenInstitute for Health Metrics and Evaluation, University of Washington, Seattle, USA.
Shachi MittalDepartment of Chemical Engineering, University of Washington, Seattle, USA.
Hmwe H KyuInstitute for Health Metrics and Evaluation, University of Washington, Seattle, USA. hmwekyu@uw.edu.ORCID http://orcid.org/0000-0002-0449-5691

Funding

Quantification of HIV burden and the biomedical, structural, and behavioral factors influencing HIV/AIDS among children and young adolescentsR01AI152721 · NIAID · UNIVERSITY OF WASHINGTON · PI KYU, HMWE HMWE · 2021 to 2025
$3.6M
Medical Research Council MR/X020258/1National Institute of Allergy and Infectious Diseases R01AI152721NIAID NIH HHS R01 AI152721
6 · The paper itself

Abstract

We investigated the association between early sexual debut and HIV infection among adolescents and young adults. Analyzing data from nationally representative Population-Based HIV Impact Assessment (PHIA) surveys in 11 African countries, the research employed a multivariate logistic regression model to assess the relationship between the early sexual debut and new HIV infections in the age group of 10-24 years. The results revealed a significant and robust association, indicating that young individuals who experienced early sexual debut were approximately 2.65 times more likely to contract HIV than those who did not, even after accounting for other variables. These findings align with prior research suggesting that early initiation of sexual activity may increase vulnerability to HIV infection due to factors such as biological susceptibility and risky behaviors like low condom use and multiple sexual partners. The implications of these findings for HIV prevention strategies are substantial, suggesting that interventions aimed at delaying sexual debut could be an effective component in reducing HIV risk for this population. Targeted sex education programs that address the risks of early sexual debut may play a pivotal role in these prevention efforts. By employing a comprehensive approach, there is a possibility to advance efforts towards ending AIDS by 2030.

Indexed as

HIV InfectionsRisk-TakingSexual BehaviorSexual PartnersAdolescentAdultAfricaAge FactorsChildCondomsFemaleHumansLogistic ModelsMaleRisk FactorsYoung AdultAdolescents and young adultsAfrican countriesEarly sexual debutNew HIV infectionPHIA surveys

Identifiers

PMID38878135
PMCPMC11199287

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.