ArticleMovement disorders : official journal of the Movement Disorder Society2024
Responsive Versus Continuous Deep Brain Stimulation for Speech in Essential Tremor: A Pilot Study.
Article in Movement disorders : official journal of the Movement Disorder Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Speech and Deep Brain Stimulation in Parkinson's Disease, Essential Tremor, and Dystonia: A Systematic Review and Meta-analysis.Movement disorders : official journal of the Movement Disorder Society · 2026Pooled it
- Decoding pre-movement neural activity from thalamic LFPs for adaptive neurostimulation in tremor patients.Neurocomputing · 2026Article
- An acoustic model of speech dysprosody in patients with Parkinson's disease.Frontiers in human neuroscience · 2025Article
- Responsive Deep Brain Stimulation: A New Hope for Controlling Stimulation-Induced Dysarthria in Essential Tremor.Movement disorders : official journal of the Movement Disorder Society · 2024Article
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
backgroundResponsive deep brain stimulation (rDBS) uses physiological signals to deliver stimulation when needed. rDBS is hypothesized to reduce stimulation-induced speech effects associated with continuous DBS (cDBS) in patients with essential tremor (ET).
objectiveTo determine if rDBS reduces cDBS speech-related side effects while maintaining tremor suppression.
methodsEight ET participants with thalamic DBS underwent unilateral rDBS. Both speech evaluations and tremor severity were assessed across three conditions (DBS OFF, cDBS ON, and rDBS ON). Speech was analyzed using intelligibility ratings. Tremor severity was scored using the Fahn-Tolosa-Marin Tremor Rating Scale (TRS).
resultsDuring unilateral cDBS, participants experienced reduced speech intelligibility (P = 0.025) compared to DBS OFF. rDBS was not associated with a deterioration of intelligibility. Both rDBS (P = 0.026) and cDBS (P = 0.038) improved the contralateral TRS score compared to DBS OFF.
conclusionsrDBS maintained speech intelligibility without loss of tremor suppression. A larger prospective chronic study of rDBS in ET is justified. © 2024 International Parkinson and Movement Disorder Society.
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