ArticleTherapeutic advances in respiratory disease
Prescriptions of opioid-containing drugs in patients with chronic cough.
Article in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Understanding the economic burden of chronic cough: a systematic literature review.BMC pulmonary medicine · 2023Pooled it
- Clinical impact and healthcare resource utilisation in patients with unexplained or refractory chronic cough: a French national population study.ERJ open research · 2026Article
- Female predominance in chronic cough: biological sex-related factors, mechanisms, and therapeutic targets-a narrative review.Frontiers in medicine · 2026Review
- The central regulatory network of cough: a cornerstone of cough management.Journal of thoracic disease · 2025Review
- Article
- Codeine prescription pattern and treatment responses in patients with chronic cough: a routinely collected institutional database analysis.Journal of thoracic disease · 2023Article
- Prevalence and Characteristics of Chronic Cough in Adults Identified by Administrative Data.The Permanente journal · 2020Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic cough (CC) affects about 10% of adults, but opioid use in CC is not well understood.
objectivesTo determine the use of opioid-containing cough suppressant (OCCS) prescriptions in patients with CC using electronic health records.
designRetrospective cohort study.
methodsThrough retrospective analysis of Midwestern U.S. electronic health records, diagnoses, prescriptions, and natural language processing identified CC - at least three medical encounters with cough, with 56-120 days between first and last encounter - and a 'non-chronic cohort'. Student's
resultsAbout 20% of 23,210 patients with CC were prescribed OCCS; odds of an OCCS prescription were twice as great in CC. In CC, OCCS drugs were ordered in 38% with Medicaid insurance and 15% with commercial insurance.
conclusionFindings identify an important role for opioids in CC, and opportunity to learn more about the drugs' effectiveness.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.