ArticleBMC chemistry2024
Determination of levofloxacin, norfloxacin, and moxifloxacin in pharmaceutical dosage form or individually using derivative UV spectrophotometry.
Article in BMC chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- UV-visible spectrophotometry in modern research: applications in adsorption, photocatalysis, catalytic reduction, sensing nanomaterials, and drug delivery.RSC advances · 2026Review
- Ferrocene-functionalized NHMikrochimica acta · 2026Article
- Eco-friendly approach for spectrofluorimetric determination of moxifloxacin in pharmaceutical formulations and biological samples using deep eutectic solvents.BMC chemistry · 2026Article
- Development and Validation of Spectrophotometric Method for Determination of Levofloxacin in Rat Plasma.Molecules (Basel, Switzerland) · 2026Article
- Development and optimization of Moxifloxacin solid lipid nanoparticles via double emulsion organic solvent free technique applying Box-Behnken experimental design.Scientific reports · 2025Article
- Dual-emission nitrogen-doped carbon dots for ratiometric and smartphone-based detection of levofloxacin.RSC advances · 2025Article
- Metal chelation approach synergized with surfactant for spectrofluorimetric assay of moxifloxacin with method greenness evaluation.BMC chemistry · 2025Article
- Determination of levofloxacin, norfloxacin, and moxifloxacin in pharmaceutical dosage form or individually using derivative UV spectrophotometry.BMC chemistry · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIn this study, first, second, third, and fourth-order derivative spectrophotometric methods utilizing the peak-zero (P-O) and peak-peak (P-P) techniques of measurement were developed for the determination of levofloxacin, norfloxacin, and moxifloxacin. These methods were applied to their combined pharmaceutical dosage form or individually for levofloxacin, norfloxacin, and moxifloxacin.
methodsLinearity was established in the concentration range of 2-20 µg/mL. The procedures are simple, quick, and precise. The developed methods are sensitive, accurate, and cost-effective, demonstrating excellent correlation coefficients (R2 = 0.9998) and mean recovery values ranging from 99.20% to 100.08%, indicating a high level of precision.
resultsThe developed approach was effectively employed to determine the levofloxacin, norfloxacin, and moxifloxacin content in commercially available pharmaceutical dosages.
conclusionsStatistical analysis and recovery tests confirmed the method's linearity and accuracy. The results suggest that this method can be utilized for routine analysis in both bulk and commercial formulations. The simplicity, accuracy, and cost-effectiveness of the developed methods make them valuable for pharmaceutical analysis.
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