ArticleBMC surgery2024
Benefits of uric acid-lowering medication after bariatric surgery in patients with gout.
Article in BMC surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of Metabolic and Bariatric Surgery on Serum Uric Acid and its Association with Renal Function, and Visceral Adiposity: A Systematic Review and Meta-Analysis.Obesity surgery · 2026Pooled it
- Impact of Bariatric Surgery on Gout Medication: a Nationwide Cohort Study.Obesity surgery · 2026Article
- A Bayesian network-based predictive model for gout onset risk: associations with traditional Chinese medicine constitution in hyperuricemic populations.Frontiers in medicine · 2026Article
- Short-term dynamics of serum uric acid and its influencing factors in patients with obesity after laparoscopic sleeve gastrectomy.BMC surgery · 2025Article
- Risk factors for early-onset hyperuricemia and gout following laparoscopic sleeve gastrectomy: a retrospective study.BMC surgery · 2025Article
- Sleeve gastrectomy ameliorates renal injury in obesity-combined hyperuricemic nephropathy mice by modulating the AMPK/Nrf2/ABCG2 pathway.Scientific reports · 2024Article
- Research progress on bariatric surgery for hyperuricemia.BMC surgery · 2024Review
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
background/purposePatients with gout are at risk for increased serum uric acid (SUA) levels and gout attacks in the short term after undergoing bariatric surgery, and the purpose of this study was to evaluate the benefits of short-term treatment with uric acid-lowering medication after bariatric surgery for the control of gout attacks and SUA levels in patients with gout.
methods71 patients who underwent SG from January 2020 to December 2022 were prospectively included. These patients were diagnosed with hyperuricemia before surgery and had a history of gout attacks. Patients were classified into a drug-treatment group (DTG, n = 32) and a non-drug-treatment group (NDTG, n = 39) according to whether they took uric acid-lowering medication after surgery. Changes in the number of gout attacks, body mass index (BMI), and SUA levels at 1 week, 1 month, 3 months, and 6 months after bariatric surgery were measured in both groups.
resultsIn the DTG, 22 patients (68.8%) experienced an increase in SUA within 1 week, 3 patients (9.4%) had an acute attack of gout within the first month, and no patients had a gout attack thereafter. In the NDTG, 35 patients (89.7%) experienced an increase in SUA within 1 week, 7 patients (17.9%) had an acute gout attack within the first month, and 4 patients (10.3%) experienced gout attacks between month 1 and month 3 postoperatively. Both groups were free of gout attacks between the 3rd and 6th postoperative month and showed a significant decrease in SUA and BMI by the sixth month.
conclusionIn patients with gout, continued use of uric acid-lowering medication after bariatric surgery is beneficial in reducing the number of gout attacks and the risk of rising SUA.
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