Evidence map›Paper›PMID 38877426›Full record

ArticleBMC gastroenterology2024

Predictive values of an immunological fecal occult blood test for the diagnosis of colorectal cancer compared using colonoscopy in symptomatic patients in Yaounde (Cameroon).

Tchuitcheu Ulrich Jovanka, Ndjitoyap Ndam Antonin Wilson, Bekolo Nga Winnie, Ngogang Marie Paule, Talla Paul, Dang Babagna Isabelle, Biwole Sida Magloire

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tchuitcheu Ulrich JovankaDepartment of Internal Medicine, Higher Institute of Medical Technology, University of Douala, Yaoundé, Cameroon.
Ndjitoyap Ndam Antonin WilsonDepartment of Internal Medicine, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon. tonindam3@yahoo.fr.ORCID http://orcid.org/0000-0002-6275-1622
Bekolo Nga WinnieDepartment of Clinical Sciences, Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.ORCID http://orcid.org/0000-0001-8499-402X
Ngogang Marie PauleDepartment of Internal Medicine, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon.
Talla PaulHepatogastroenterology Unit, Internal Medicine Service, Yaoundé General Hospital, Yaoundé, Cameroon.
Dang Babagna IsabelleHepatogastroenterology Unit, Internal Medicine Service, Yaoundé General Hospital, Yaoundé, Cameroon.
Biwole Sida MagloireDepartment of Internal Medicine, Higher Institute of Medical Technology, University of Douala, Yaoundé, Cameroon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe predictive value of immunological fecal occult blood (iFOB) testing for the screening of colorectal cancer has been well described in the Western world. However, its relevance in Sub-Saharan Africa (SSA) is not well evaluated. It could be altered by the other causes of lower gastrointestinal bleeding such as parasitic infections. The aim of this study was to highlight the performance of an iFOB test for the prediction of colorectal cancer (CRC) during colonoscopy in SSA. METHODOLOGY: We conducted an analytical cross-sectional study in two digestive endoscopic centers of Yaoundé (Cameroon) from the 1

resultsWe included 103 patients during the study period with a male predominance and a sex ratio of 1.7. The median age [IQR] was 52 [38-65] years (range 1 - 84 years). The most common colonoscopic lesions were polyps in 23 patients (22.3%), CRC in 17 patients (16.5%) and hemorrhoids in 15 patients (14.6%). Patients testing positive for iFOB test accounted for 43.7% (45 patients). Among these patients, 31.1% (14 patients) had a CRC. The Se of the occult blood test for CRC detection was calculated to be 82.3% (95%CI: 56.7-96.2); the Sp was 63.9% (95% CI: 53-74); the PPV was 31.1% (95% CI: 24-39) and the NPV was 94.8% (95% CI: 86.6-98.1).

conclusionThe iFOB test has a good NPV, but a poor PPV for the diagnosis of CRC in our study.

Indexed as

ColonoscopyColorectal NeoplasmsEarly Detection of CancerOccult BloodPredictive Value of TestsAdolescentAdultAgedAged, 80 and overCameroonChildCross-Sectional StudiesFemaleHumansMaleMiddle AgedCameroonColorectal cancerDiagnosisImmunological fecal occult blood testPredictive valueSymptomatic patients

Identifiers

PMID38877426
PMCPMC11179338

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