Evidence map›Paper›PMID 38877000›Full record

ArticleNature communications2024

International and regional spread of carbapenem-resistant Klebsiella pneumoniae in Europe.

Mabel Budia-Silva, Tomislav Kostyanev, Stefany Ayala-Montaño, Jose Bravo-Ferrer Acosta, Maria Garcia-Castillo, Rafael Cantón, Herman Goossens, Jesus Rodriguez-Baño, Hajo Grundmann, Sandra Reuter

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
114citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

114 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Carbapenem-ResistantMicroorganisms · 2026
    Review
  7. Review
  8. Emergence and Dissemination of NDM+OXA-48-like Co-ProducingAntibiotics (Basel, Switzerland) · 2026
    Article
  9. Rectal Surveillance for Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2026
    Article
  10. Article
  11. KPC-producing Klebsiella pneumoniae in Switzerland from 2024 to 2025: comparative genomics and cefiderocol resistance mechanisms analyses.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Multicenter Point-Prevalence Study of Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2026
    Article
  17. Article
  18. Article
  19. Article
  20. Article

54 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mabel Budia-SilvaInstitute for Infection Prevention and Control, University of Freiburg - Medical Center, Freiburg, Germany.
Tomislav KostyanevLaboratory of Medical Microbiology, University of Antwerp, Antwerp, Belgium.
Stefany Ayala-MontañoInstitute for Infection Prevention and Control, University of Freiburg - Medical Center, Freiburg, Germany.
Jose Bravo-Ferrer AcostaUnidad Clínica de Enfermedades Infecciosas y Microbiología, Instituto de Biomedicina de Sevilla (IBiS)/CSIC, Hospital Universitario Virgen Macarena; and Departamento de Medicina, Universidad de Sevilla, Seville, Spain.ORCID http://orcid.org/0000-0002-4638-5001
Maria Garcia-CastilloServicio de Microbiología, Hospital Universitario Ramón y Cajal and Instituto Ramón y Caja de Investigación Sanitaria (IRYCIS), Madrid, Spain.
Rafael CantónServicio de Microbiología, Hospital Universitario Ramón y Cajal and Instituto Ramón y Caja de Investigación Sanitaria (IRYCIS), Madrid, Spain.ORCID http://orcid.org/0000-0003-1675-3173
Herman GoossensLaboratory of Medical Microbiology, University of Antwerp, Antwerp, Belgium.
Jesus Rodriguez-BañoUnidad Clínica de Enfermedades Infecciosas y Microbiología, Instituto de Biomedicina de Sevilla (IBiS)/CSIC, Hospital Universitario Virgen Macarena; and Departamento de Medicina, Universidad de Sevilla, Seville, Spain.ORCID http://orcid.org/0000-0001-6732-9001
Hajo GrundmannInstitute for Infection Prevention and Control, University of Freiburg - Medical Center, Freiburg, Germany.ORCID http://orcid.org/0000-0002-9971-522X
Sandra ReuterInstitute for Infection Prevention and Control, University of Freiburg - Medical Center, Freiburg, Germany. sandra.reuter@uniklinik-freiburg.de.ORCID http://orcid.org/0000-0003-1672-5789

Funding

Bundesministerium für Bildung und Forschung (Federal Ministry of Education and Research) 01KI2018Innovative Medicines Initiative (IMI) 115523Innovative Medicines Initiative (IMI) 115620
6 · The paper itself

Abstract

Carbapenem-resistant Klebsiella pneumoniae (CRKP) are of particular concern due to the spread of antibiotic resistance genes associated with mobile genetic elements. In this study, we collected 687 carbapenem-resistant strains recovered among clinical samples from 41 hospitals in nine Southern European countries (2016-2018). We identified 11 major clonal lineages, with most isolates belonging to the high-risk clones ST258/512, ST101, ST11, and ST307. bla

Indexed as

Anti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsKlebsiella InfectionsKlebsiella pneumoniaeCarbapenem-Resistant EnterobacteriaceaeEuropeHumansMicrobial Sensitivity TestsMultilocus Sequence TypingAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasescarbapenemaseCarbapenems

Identifiers

PMID38877000
PMCPMC11178878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.