Evidence map›Paper›PMID 38876162›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2024

Coxsackievirus A24 causing acute conjunctivitis in a 2023 outbreak in Vietnam.

Huy Tran, Thao Ha, Linh Hoang, Yen Tran, Kevin Ruder, Lina Zhong, Cindi Chen, YuHeng Liu, Danny Yu, Thomas Abraham and 7 more

Abstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Huy TranHai Yen Vision Institute, Ho Chi Minh City, Vietnam.
Thao HaHai Yen Vision Institute, Ho Chi Minh City, Vietnam.
Linh HoangHai Yen Vision Institute, Ho Chi Minh City, Vietnam.
Yen TranHai Yen Vision Institute, Ho Chi Minh City, Vietnam.
Kevin RuderFrancis I. Proctor Foundation, University of California, San Francisco, USA.
Lina ZhongFrancis I. Proctor Foundation, University of California, San Francisco, USA.
Cindi ChenFrancis I. Proctor Foundation, University of California, San Francisco, USA.
YuHeng LiuFrancis I. Proctor Foundation, University of California, San Francisco, USA.
Danny YuFrancis I. Proctor Foundation, University of California, San Francisco, USA.
Thomas AbrahamFrancis I. Proctor Foundation, University of California, San Francisco, USA.
Armin HinterwirthFrancis I. Proctor Foundation, University of California, San Francisco, USA.
Michael DeinerDepartment of Ophthalmology, University of California, San Francisco, USA.
Travis C PorcoDepartment of Ophthalmology, University of California, San Francisco, USA.
Thomas M LietmanFrancis I. Proctor Foundation, University of California, San Francisco, USA; Department of Ophthalmology, University of California, San Francisco, USA.
Thuy DoanFrancis I. Proctor Foundation, University of California, San Francisco, USA; Department of Ophthalmology, University of California, San Francisco, USA. Electronic address: Thuy.Doan@ucsf.edu.
Gerami D SeitzmanFrancis I. Proctor Foundation, University of California, San Francisco, USA; Department of Ophthalmology, University of California, San Francisco, USA.
SCORPIO Study Group

Funding

Rapid-Prototyping and Design CoreP30EY002162 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LAMBA, DEEPAK ASHOK · 1985 to 2024
$16.8M
UCSF-Proctor Clinician Vision Scholars K12 ProgramK12EY031372 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI THOMAS M LIETMAN, Yvonne Ou · 2020 to 2026
$3.9M
Seasonal Conjunctivitis Outbreak Reporting for Prevention and Improved Outcomes (SCORPIO)R01EY032041 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DOAN, THUY A · 2021 to 2025
$2.0M
Improving Corneal Ulcer Outcomes with Unbiased Pathogen and Antimicrobial Resistance DetectionR01EY032861 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DOAN, THUY A · 2022 to 2025
$1.6M
NEI NIH HHS K12 EY031372NEI NIH HHS P30 EY002162NEI NIH HHS R01 EY032041NEI NIH HHS R01 EY032861
6 · The paper itself

Abstract

objectivesTo determine the associated pathogen during the 2023 conjunctivitis outbreak in Vietnam

methodsRNA-sequencing was used to identify pathogens before and during the outbreak.

results24 patients with infectious conjunctivitis between March and October 2023 from Hai Yen Vision Institute in Vietnam were swabbed. Coxsackievirus A24v was the most common pathogen identified. Phylogenetic analysis of these strains demonstrates similarities to the Coxsackievirus identified in the 2022 India outbreak. Human adenovirus D was also circulating. Ocular findings of tearing, purulence, and itching were common in this outbreak.

conclusionsMultiple viruses can co-circulate during conjunctivitis outbreaks. Hemorrhagic conjunctivitis, commonly associated with coxsackievirus conjunctivitis, was not a common clinical sign in this outbreak. Repeat genetic surveillance, with the notable inclusion of RNA virus detection strategies, is important for outbreak detection.

Indexed as

Coxsackievirus InfectionsDisease OutbreaksPhylogenyAdolescentAdultChildChild, PreschoolConjunctivitis, Acute HemorrhagicConjunctivitis, ViralFemaleHumansMaleMiddle AgedVietnamYoung AdultConjunctivitisCoxsackievirusEpidemicKeratoconjunctivitis (EKC)Vietnam

Identifiers

PMID38876162
PMCPMC11847566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.