Evidence map›Paper›PMID 38875608›Full record

ArticleOptics letters2024

Two-site microendoscopic imaging probe for simultaneous three-dimensional imaging at two anatomic locations in tissues.

Guigen Liu, Sebastian W Ahn, Jeon Woong Kang, Sharath Bhagavatula, Destiny Matthew, Samantha Martin, Courtney Marlin, Peter T C So, Guillermo J Tearney, Oliver Jonas

Abstract read
In one paragraph

Article in Optics letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Guigen Liu
Sebastian W Ahn
Jeon Woong Kang
Sharath Bhagavatula
Destiny Matthew
Samantha Martin
Courtney Marlin
Peter T C So
Guillermo J Tearney
Oliver Jonas

Funding

Wide-Field Short-Wave Infrared (SWIR) multiphoton (MP) tissue imagingP41EB015871 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SO, PETER T. · 2012 to 2021
$11.3M
TRD 3 - Enabling Technologies for Intraprocedural GuidanceP41EB028741 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI Nobuhiko Hata, CLARE M TEMPANY · 2021 to 2026
$10.7M
Dynamic µOCT for cellular tissue phenotypingR01CA265742 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI JONAS, OLIVER, TEARNEY, GUILLERMO J · 2021 to 2025
$3.0M
A tethered capsule endoscopic-endomicroscopic (TEEM) approach for improving upper GI tract diagnosisR01DK117236 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI TEARNEY, GUILLERMO J, WOLFSEN, HERBERT · 2019 to 2022
$2.6M
Implantable microdevices with integrated optical imaging for high-throughput in situ tumor response and drug sensitivity measurementR37CA224144 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI JONAS, OLIVER · 2018 to 2023
$2.4M
Four-dimensional multi-modality microimaging-microdevice system for high throughput drug screening in vivoK25EB032900 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI LIU, GUIGEN · 2022 to 2025
$694k
NCI NIH HHS R01 CA265742NCI NIH HHS R37 CA224144NIBIB NIH HHS K25 EB032900NIBIB NIH HHS P41 EB015871NIBIB NIH HHS P41 EB028741NIDDK NIH HHS R01 DK117236
6 · The paper itself

Abstract

Systems that can image in three dimensions at cellular resolution and across different locations within an organism may enable insights into complex biological processes, such as immune responses, for which a single location measurement may be insufficient. In this Letter, we describe an in vivo two-site imaging probe (TIP) that can simultaneously image two anatomic sites with a maximum separation of a few centimeters. The TIP consists of two identical bendable graded index (GRIN) lenses and is demonstrated by a two-photon two-color fluorescence imaging system. Each GRIN lens has a field of view of 162 ×

Indexed as

Imaging, Three-DimensionalAnimalsCell Line, TumorEndoscopyHumansMice

Identifiers

PMID38875608
PMCPMC11298057

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.