Evidence map›Paper›PMID 38874885›Full record

ArticleHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2024

Central Obesity is Associated with Increased Left Ventricular Maximal Wall Thickness and Intrathoracic Adipose Tissue Measured with Cardiac Magnetic Resonance.

Jarkko Marttila, Petri Sipola, Auni Juutilainen, Saara Sillanmäki, Marja Hedman, Johanna Kuusisto

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Article in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Cardiac Organ Damage in Young Adults with Cryptogenic Ischaemic Stroke: The SECRETO Study.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jarkko MarttilaDiagnostic Imaging Center, Kuopio University Hospital, 70210, Kuopio, Finland.ORCID http://orcid.org/0000-0003-0181-9926
Petri SipolaUniversity of Eastern Finland, Kuopio, Finland.ORCID http://orcid.org/0000-0002-1954-1945
Auni JuutilainenInstitute of Clinical Medicine, University of Eastern Finland, 70210, Kuopio, Finland.ORCID http://orcid.org/0000-0003-0271-4368
Saara SillanmäkiDiagnostic Imaging Center, Kuopio University Hospital, 70210, Kuopio, Finland. saara.sillanmaki@pshyvinvointialue.fi.ORCID http://orcid.org/0000-0002-8130-3219
Marja HedmanDiagnostic Imaging Center, Kuopio University Hospital, 70210, Kuopio, Finland.ORCID http://orcid.org/0000-0003-1318-8287
Johanna KuusistoDepartment of Medicine, Kuopio University Hospital, Kuopio, Finland.ORCID http://orcid.org/0000-0001-6550-3176

Funding

Research Committee of the Kuopio University Hospital Catchment Area for State Research Funding 5063586
6 · The paper itself

Abstract

introductionCentral obesity (CO), characterized by an increased waist circumference increases the risk of cardiovascular disease (CVD) and morbidity, yet the underlying mechanisms are not fully understood. CO is often associated with general obesity, hypertension, and abnormal glucose tolerance, confounding the independent contribution of CO to CVD.

aimWe investigated the relationship of CO (without associated disorders) with left ventricular (LV) characteristics and intrathoracic adipose tissue (IAT) by cardiac magnetic resonance.

methodsLV characteristics, epicardial (EAT), and mediastinal adipose tissue (MAT) were measured from 29 normoglycemic, normotensive males with CO but without general obesity (waist circumference >100 cm, body mass index (BMI) <30 kg/m

resultsLV maximal wall thickness (LVMWT) and IAT but not LV mass or volumes were increased in CO subjects compared to controls (LVMWT, 12.3±1.2 vs. 10.7±1.5 mm, p < 0.001; EAT, 5.5±3.0 vs. 2.2±2.0 cm

conclusionsCO independent of BMI is associated with LV hypertrophy and intrathoracic adipose tissue contributing to cardiovascular burden.

Indexed as

AdiposityHypertrophy, Left VentricularObesity, AbdominalPredictive Value of TestsVentricular Function, LeftVentricular RemodelingAdipose TissueAdultBody Mass IndexCase-Control StudiesCross-Sectional StudiesHumansMagnetic Resonance ImagingMagnetic Resonance Imaging, CineMaleMiddle AgedCardiovascular magnetic resonanceCentral obesityIntrathoracic adipose tissueLeft ventricular hypertrophyLeft ventricular wall thicknessWaist-to-hip ratio

Identifiers

PMID38874885
PMCPMC11322205

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.